Identification of Evidence-Based Interventions for Promoting HIV Medication Adherence: Findings from a Systematic Review of U.S.-Based Studies, 1996–2011

Details

• Alternative Title:
  AIDS Behav
• Personal Author:
  Charania, Mahnaz R. ; Marshall, Khiya J. ; Lyles, Cynthia M. ; Crepaz, Nicole ; Kay, Linda S. ; Koenig, Linda J. ; Weidle, Paul J. ; Purcell, David W.
• Corporate Authors:
  HIV/AIDS Prevention Research Synthesis (PRS) Team
• Description:
  A systematic review was conducted to identify evidence-based interventions (EBIs) for increasing HIV medication adherence behavior or decreasing HIV viral load among persons living with HIV (PLWH). We conducted automated searches of electronic databases (i.e., MEDLINE, EMBASE, PsycINFO, CINAHL) and manual searches of journals, reference lists, and listservs. Interventions were eligible for the review if they were U.S.-based, published between 1996 and 2011, intended to improve HIV medication adherence behaviors of PLWH, evaluated the intervention using a comparison group, and reported outcome data on adherence behaviors or HIV viral load. Each intervention was evaluated on the quality of study design, implementation, analysis, and strength of findings. Of the 65 eligible interventions, 10 are EBIs. The remaining 55 interventions failed to meet the efficacy criteria primarily due to null findings, small sample sizes, or low retention rates. Research gaps and future directions for development of adherence EBIs are discussed.
• Subjects:
  Adult AIDS Vaccines Condoms Directive Counseling Health Knowledge, Attitudes, Practice Health Policy HIV Infections Homosexuality, Male Humans Male Medication Adherence Risk-Taking Risk Reduction Behavior Sexual Behavior United States

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• Keywords:
  Antiretroviral Therapy Evidence-based HIV/AIDS Intervention Medication Adherence
• Source:
  AIDS Behav. 18(4):646-660
• Pubmed ID:
  24043269
• Pubmed Central ID:
  PMC4701030
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHSUnited States/
• Volume:
  18
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:97ccb894413d07c45b1c026978496684f5aae048078c04ce5d9ca6046386e03d
• Download URL:
  https://stacks.cdc.gov/view/cdc/37259/cdc_37259_DS1.pdf
• File Type:
  [PDF - 421.67 KB ]