National decision-making for the introduction of new vaccines: A systematic review, 2010–2020

Details

• Alternative Title:
  Vaccine
• Personal Author:
  Donadel, Morgane ; Panero, Maria Susana ; Ametewee, Lynnette ; Shefer, Abigail M.
• Description:
  Background:
  
  Competing priorities make using a transparent and evidence-based approach important when deciding to recommend new vaccines. We conducted a literature review to document the processes and frameworks for national decision-making on new vaccine introductions and explored which key features have evolved since 2010.
  
  Methods:
  
  We searched literature published on policymaking related to vaccine introduction from March 2010 to August 2020 in six databases. We screened articles for eligibility with the following exclusion criteria: non-human or hypothetical vaccines, the sole focus on economic evaluation or decision to adopt rather than policy decision-making. We employed nine broad categories of criteria from the 2012 review for categorization and abstracted data on the country, income level, vaccine, and other relevant criteria.
  
  Results:
  
  Of the 3808 unique references screened, 116 met eligibility criteria and were classified as: a) framework of vaccine adoption decision-making (27), b) studies that analyse empirical data on or examples of vaccine adoption decision-making (45), c) theoretical and empirical articles that provide insights into the vaccine policymaking process (44 + 17 already included in the previous categories). Commonly reported criteria for decision-making were the burden of disease; vaccine efficacy/effectiveness, safety; impact on health and non-health outcomes; economic evaluation and cost-effectiveness of alternative interventions. Programmatic and acceptability aspects were not as often considered. Most (50; 82%) of the 61 articles describing the process of vaccine introduction policymaking highlighted the role of country, regional, or global evidence-informed recommendations and a robust national governance as enabling factors for vaccine adoption.
  
  Conclusions:
  
  The literature on vaccine adoption decision-making has expanded since 2010. We found that policymakers and expert advisory committee members (e.g., National Immunization Technical Advisory Group [NITAG]) increasingly value the interventions based on economic evaluations. The results of this review could guide discussions on evidence-informed immunization decision-making among country, sub-regional, and regional stakeholders.
  
  
• Subjects:
  Article Evidence-based Decision-making Health Policy Health System Strengthening Immunization Immunization Programs Infectious Diseases Systematic Review Vaccination Vaccine Policy Vaccines

  More +
• Source:
  Vaccine. 39(14):1897-1909
• Pubmed ID:
  33750592
• Pubmed Central ID:
  PMC10370349
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  39
• Issue:
  14
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:7332bd0fcd715e134d54fa29a891a7992503d4d948926957e45eb401eaa7f38a
• Download URL:
  https://stacks.cdc.gov/view/cdc/131471/cdc_131471_DS1.pdf
• File Type:
  [PDF - 359.23 KB ]