Low Susceptibility of Pigs against Experimental Infection with HPAI Virus H5N1 Clade 2.3.4.4b

Graaf, Annika; Piesche, Ronja; Sehl-Ewert, Julia; Grund, Christian; Pohlmann, Anne; Beer, Martin; Harder, Timm

doi:10.3201/eid2907.230296

i

Low Susceptibility of Pigs against Experimental Infection with HPAI Virus H5N1 Clade 2.3.4.4b

Supporting Files Public Domain

7 2023
By Graaf, Annika ; Piesche, Ronja ; Sehl-Ewert, Julia ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Graaf, Annika ; Piesche, Ronja ; Sehl-Ewert, Julia ; Grund, Christian ; Pohlmann, Anne ; Beer, Martin ; Harder, Timm
Description:

We found that nasal and alimentary experimental exposure of pigs to highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b was associated with marginal viral replication, without inducing any clinical manifestation or pathological changes. Only 1 of 8 pigs seroconverted, pointing to high resistance of pigs to clade 2.3.4.4b infection.
Subjects:

Animals Influenza A Virus Influenza A Virus, H5N1 Subtype Influenza In Birds Swine Virus Replication
Source:

Emerg Infect Dis. 2023; 29(7):1492-1495
Pubmed ID:

37347930
Pubmed Central ID:

PMC10310384
Document Type:

Journal Article
Genre:

Research Letter
Volume:

29
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:b2b6e53634ebf42d2c177931ffe6e18164b4e6fd56c9f3a42d9d6a065ffd5d2b
Download URL:

https://stacks.cdc.gov/view/cdc/130826/cdc_130826_DS1.pdf
File Type:

[PDF - 810.91 KB ]

File Language:

English

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