Isotemporal Associations of Device-Measured Sedentary Time and Physical Activity with Cardiac-Autonomic Regulation in Previously Pregnant Women

Details

• Alternative Title:
  Int J Behav Med
• Personal Author:
  Alansare, Abdullah Bandar ; Gibbs, Bethany Barone ; Holzman, Claudia ; Jennings, J. Richard ; Kline, Christopher E. ; Nagle, Elizabeth ; Catov, Janet M.
• Description:
  Background:
  
  High sedentary time (ST) and low physical activity may increase cardiovascular risk, potentially though cardiac-autonomic dysregulation. This study investigated associations of statistically exchanging device-measured ST and physical activity with measures of cardiac-autonomic regulation in previously pregnant women.
  
  Methods:
  
  This cross-sectional, secondary analysis included 286 women (age=32.6±5.7 yrs; 68% white) measured 7-15 years after delivery. ST and light (LPA), moderate (MPA), vigorous (VPA), and moderate-to-vigorous (MVPA) intensity physical activity were measured by ActiGraph GT3X. ST was further partitioned into long (≥30 minutes) and short (<30 minutes) bouts. MVPA was also partitioned into long (≥10-minute) and short (<10-minute) bouts. Cardiac-autonomic regulation was assessed by heart rate variability (HRV) (resting heart rate, natural log transformed standard deviation of normal R-R intervals [lnSDNN], natural log-transformed root mean square of successive differences [lnRMSSD]) from a 5-minute seated ECG. Progressive isotemporal substitution models adjusted for confounders. Sensitivity analyses removed women with related underlying medical conditions and who did not meet respiration rate criteria.
  
  Results:
  
  Initial analyses found no significant associations with HRV when exchanging 30 minutes of ST and physical activity (p>0.05). Yet, replacing long- and short-bout ST with 30 minutes of long-bout MVPA yielded significantly higher (healthier) lnRMSSD (B=0.063±0.030 and B=0.056±0.027, respectively; both p<0.05). Sensitivity analyses strengthened these associations and yielded further associations of higher lnSDNN and lnRMSSD when replacing 30 minutes of short-bout MVPA with equivalent amounts of long-bout MVPA (B=0.074±0.037 and B=0.091±0.046, respectively).
  
  Conclusion:
  
  Replacing ST with long-bout MVPA is a potential strategy to improve cardiac-autonomic function in previously pregnant women.
  
  
• Subjects:
  Accelerometry Adult Cross-Sectional Studies Exercise Female Heart Rate Humans Pregnancy Pregnant Women Sedentary Behavior
• Keywords:
  Exercise Heart Rate Variability Isotemporal Substitution Physical Behaviors Vagal Tone
• Source:
  Int J Behav Med. 30(4):497-508
• Pubmed ID:
  35819720
• Pubmed Central ID:
  PMC9832172
• Document Type:
  Journal Article
• Funding:
  R01 HL103825/HL/NHLBI NIH HHSUnited States/ ; R01 HD034543/HD/NICHD NIH HHSUnited States/ ; U01 DP000143/DP/NCCDPHP CDC HHSUnited States/
• Volume:
  30
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:cde7777c8d97d571b56934b5ca920236d69dd0ae5b0d449010e826ab227218ce776891d4f520209a12e2bc08544b84120cdbae9e7ed59e72c0a8e305a04e9f77
• Download URL:
  https://stacks.cdc.gov/view/cdc/130717/cdc_130717_DS1.pdf
• File Type:
  [PDF - 510.46 KB ]