Isolated Ocular Mpox without Skin Lesions, United States

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Nguyen, Minh T. ; Mentreddy, Akshay ; Schallhorn, Julie ; Chan, Matilda ; Aung, Su ; Doernberg, Sarah B. ; Babik, Jennifer ; Miles, Kevin ; Yang, Katherine ; Lydon, Emily ; Minter, Daniel J. ; Gonzales, John ; Shantha, Jessica ; Doan, Thuy ; Seitzman, Gerami D.
• Description:
  We report a case of a 53-year-old HIV-negative patient in San Francisco, California, USA, with no classic mpox prodromal symptoms or skin lesions who experienced fulminant, vision-threatening scleritis, keratitis, and uveitis. Deep sequence analysis identified monkeypox virus RNA in the aqueous humor. We confirmed the virus on the cornea and sclera by PCR.
• Subjects:
  California Eye Infection Face Humans Isolated Ocular Mpox Without Skin Lesions, United States Middle Aged Monkeypox Monkeypox Virus Mpox Orthoviruses Polymerase Chain Reaction Prodromal Symptoms Research Letter RNA, Viral United States Viruses

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• Source:
  Emerg Infect Dis. 2023; 29(6):1285-1288
• Pubmed ID:
  37130504
• Pubmed Central ID:
  PMC10202873
• Document Type:
  Journal Article
• Volume:
  29
• Issue:
  6
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:751fb9bdec801b740524ec4f0bd7f4290e0e955181d094dcd022707f6ee7b2f3
• Download URL:
  https://stacks.cdc.gov/view/cdc/129715/cdc_129715_DS1.pdf
• File Type:
  [PDF - 776.00 KB ]