Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Hui, Kenrie P.Y. ; Ho, John C.W. ; Ng, Ka-Chun ; Cheng, Samuel M.S. ; Sit, Ko-Yung ; Au, Timmy W.K. ; Poon, Leo L.M. ; Nicholls, John M. ; Peiris, Malik ; Chan, Michael C.W.
• Description:
  Human infection with avian influenza A(H3N8) virus is uncommon but can lead to acute respiratory distress syndrome. In explant cultures of the human bronchus and lung, novel H3N8 virus showed limited replication efficiency in bronchial and lung tissue but had a higher replication than avian H3N8 virus in lung tissue.
• Subjects:
  Animals Bronchi Humans Influenza, Human Influenza A Virus, H3N8 Subtype Lung Orthomyxoviridae Infections Virus Replication
• Source:
  Emerg Infect Dis. 2023; 29(6):1210-1214
• Pubmed ID:
  37095078
• Pubmed Central ID:
  PMC10202868
• Document Type:
  Journal Article
• Genre:
  Dispatch
• Place as Subject:
  China
• Volume:
  29
• Issue:
  6
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:0caee7707c60e68957f1b91cb0562a5cd6b3a4499c37903fd9624f84d640ef38
• Download URL:
  https://stacks.cdc.gov/view/cdc/129701/cdc_129701_DS1.pdf
• File Type:
  [PDF - 2.37 MB ]