Influence of Sex and Sex-Based Disparities on Prevalent Tuberculosis, Vietnam, 2017–2018

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Nguyen, Hai Viet ; Brals, Daniella ; Tiemersma, Edine ; Gasior, Robert ; Nguyen, Nhung Viet ; Nguyen, Hoa Binh ; Van Nguyen, Hung ; Le Thi, Ngoc Anh ; Cobelens, Frank
• Description:
  To assess sex disparities in tuberculosis in Vietnam, we conducted a nested, case-control study based on a 2017 tuberculosis prevalence survey. We defined the case group as all survey participants with laboratory-confirmed tuberculosis and the control group as a randomly selected group of participants with no tuberculosis. We used structural equation modeling to describe pathways from sex to tuberculosis according to an a priori conceptual framework. Our analysis included 1,319 participants, of whom 250 were case-patients. We found that sex was directly associated with tuberculosis prevalence (adjusted odds ratio for men compared with women 3.0 [95% CI 1.7-5.0]) and indirectly associated through other domains. The strong sex difference in tuberculosis prevalence is explained by a complex interplay of factors relating to behavioral and environmental risks, access to healthcare, and clinical manifestations. However, after controlling for all those factors, a direct sex effect remains that might be caused by biological factors.
• Subjects:
  Bacteria Case-Control Studies Epidemiology Female Humans Influence Of Sex And Sex-Based Disparities On Prevalent Tuberculosis, Vietnam, 2017–2018 Male Nested Case-control Study Prevalence Research Sex-based Disparities Surveys And Questionnaires Tuberculosis Tuberculosis And Other Mycobacteria Vietnam

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• Source:
  Emerg Infect Dis. 2023; 29(5):967-976
• Pubmed ID:
  37081548
• Pubmed Central ID:
  PMC10124636
• Document Type:
  Journal Article
• Volume:
  29
• Issue:
  5
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:4c0d48ca2ce44cc2bf70b84f8cd098e857e2ef40471f3ce3e273e5d2124e04b0
• Download URL:
  https://stacks.cdc.gov/view/cdc/129099/cdc_129099_DS1.pdf
• File Type:
  [PDF - 1.56 MB ]