Genome Analysis of Triploid Hybrid Leishmania Parasite from the Neotropics

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Van den Broeck, Frederik ; Heeren, Senne ; Maes, Ilse ; Sanders, Mandy ; Cotton, James A. ; Cupolillo, Elisa ; Alvarez, Eugenia ; Garcia, Lineth ; Tasia, Maureen ; Marneffe, Alice ; Dujardin, Jean-Claude ; Van der Auwera, Gert
• Description:
  We discovered a hybrid Leishmania parasite in Costa Rica that is genetically similar to hybrids from Panama. Genome analyses demonstrated the hybrid is triploid and identified L. braziliensis and L. guyanensis-related strains as parents. Our findings highlight the existence of poorly sampled Leishmania (Viannia) variants infectious to humans.
• Subjects:
  Animals Belgium Costa Rica Cutaneous Parasites Genetics Genome Analysis Of Triploid Hybrid Leishmania Parasite From The Neotropics Genomics Humans Interspecific Hybridization Leishmania Leishmaniasis Leishmaniasis, Cutaneous Panama Parasites Research Letter Triploidy

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• Source:
  Emerg Infect Dis. 2023; 29(5):1076-1078
• Pubmed ID:
  37081624
• Pubmed Central ID:
  PMC10124652
• Document Type:
  Journal Article
• Volume:
  29
• Issue:
  5
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:9c74a6a448f54243ebd415468e3e6862ced648fe6afb9492aadc3dc1fd65aa7d
• Download URL:
  https://stacks.cdc.gov/view/cdc/129098/cdc_129098_DS1.pdf
• File Type:
  [PDF - 477.95 KB ]