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Healthy vaccinee bias and MenB-FHbp vaccine effectiveness against gonorrhea
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6 01 2023
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Source: Sex Transm Dis. 50(6):e8-e10
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Alternative Title:Sex Transm Dis
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Description:Observational studies demonstrated 30% to 40% effectiveness of outer-membrane vesicle (OMV) meningococcal serogroup B vaccines against gonorrhea. To explore whether healthy vaccinee bias influenced such findings, we examined the effectiveness of MenB-FHbp, a non-OMV vaccine that is not protective against gonorrhea. MenB-FHbp was ineffective against gonorrhea. Healthy vaccinee bias likely did not confound earlier studies of OMV vaccines.
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Pubmed ID:36863060
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Pubmed Central ID:PMC10175191
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