Reactivation of Chagas disease in a bone marrow transplant patient: case report and review of screening and management

Details

• Alternative Title:
  Transpl Infect Dis
• Personal Author:
  Guiang, K.M.U. ; Cantey, P. ; Montgomery, S.P. ; Ailawadhi, S. ; Qvarnstrom, Y. ; Price, T. ; Blodget, E.
• Description:
  We report a patient with an autologous stem cell transplant and history of residence in a Chagas disease (CD) endemic area who developed Chagas reactivation after induction for transplantation. We recommend that patients at risk for CD be screened before transplantation, and patients found to have chronic infection be monitored for reactivation post transplant.
• Subjects:
  • Antibodies, Protozoan
  • Bone Marrow Transplantation
  • Chagas Disease
  • Female
  • Humans
  • Middle Aged
  • Multiple Myeloma
  • Polymerase Chain Reaction
  • Recurrence
  • Transplantation Conditioning
  More +
• Keywords:
  • Chagas disease
  • Trypanosoma cruzi
  • transplant
  • parasites
  • stem cell transplant
  • reactivation Chagas
• Source:
  Transpl Infect Dis. 15(6):E264-E267
• Pubmed ID:
  24147999
• Pubmed Central ID:
  PMC10166063
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  15
• Issue:
  6
• Download URL:
  https://stacks.cdc.gov/view/cdc/128315/cdc_128315_DS1.pdf
• File Type:
  [PDF - 52.17 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:fdfb560c897a7a46a2c2e530313effe6fb3143a6206500d02a570e4549e1d88a03b48671694d9dfda46ff12848c9d19def72642db4cccf2be96ea683c322d7a2