Multicenter Retrospective Study of Vascular Infections and Endocarditis Caused by Campylobacter spp., France

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Tinévez, Claire ; Lehours, Philippe ; Ranc, Anne-Gaëlle ; Belaroussi, Yaniss ; Cazanave, Charles ; Puges, Mathilde ; Velardo, Fanny ; Dubois, Damien ; Neuwirth, Catherine ; Pailhoriès, Hélène ; Dorel, Marie ; Hery-Arnaud, Genevieve ; Join-Lambert, Olivier ; Gras, Emmanuelle ; Corvec, Stéphane ; Codde, Cyrielle ; Fournier, Damien ; Boijout, Hugo ; Doat, Violaine ; Bouard, Leslie ; Lagneaux, Anne-Sophie ; Pichon, Maxime ; Couzigou, Célia ; Letellier, Claire ; Lemaignen, Adrien ; Bille, Emmanuelle ; Bérard, Xavier ; Caradu, Caroline ; Webster, Claire ; Neau, Didier
• Corporate Authors:
  for the Campylobacteremia Study Group
• Description:
  The incidence of campylobacteriosis has substantially increased over the past decade, notably in France. Secondary localizations complicating invasive infections are poorly described. We aimed to describe vascular infection or endocarditis caused by Campylobacter spp. We included 57 patients from a nationwide 5-year retrospective study on Campylobacter spp. bacteremia conducted in France; 44 patients had vascular infections, 12 had endocarditis, and 1 had both conditions. Campylobacter fetus was the most frequently involved species (83%). Antibiotic treatment involved a β-lactam monotherapy (54%) or was combined with a fluoroquinolone or an aminoglycoside (44%). The mortality rate was 25%. Relapse occurred in 8% of cases and was associated with delayed initiation of an efficient antimicrobial therapy after the first symptoms, diabetes, and coexistence of an osteoarticular location. Cardiovascular Campylobacter spp. infections are associated with a high mortality rate. Systematically searching for those localizations in cases of C. fetus bacteremia may be warranted.
• Subjects:
  Anti-Bacterial Agents Bacteremia Bacteria Bacterial Infections Campylobacter Campylobacter Fetus Campylobacter Infections Campylobacter Spp. Endocarditis France Graft Infections Humans Infectious Aortitis Multicenter Retrospective Study Of Vascular Infections And Endocarditis Caused By Campylobacter Spp., France Multicenter Studies As Topic Non-HACEK Endocarditis Retrospective Studies Synopsis Thrombophlebitis

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• Source:
  Emerg Infect Dis. 2023; 29(3):484-492
• Pubmed ID:
  36823023
• Pubmed Central ID:
  PMC9973684
• Document Type:
  Journal Article
• Volume:
  29
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:372d9bb61a77cda5dee4d3b5567e64d93d26cfccbc03655bbf9d6f3df6192109
• Download URL:
  https://stacks.cdc.gov/view/cdc/127666/cdc_127666_DS1.pdf
• File Type:
  [PDF - 711.66 KB ]