Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Vauhkonen, Hanna ; Kallio-Kokko, Hannimari ; Hiltunen-Back, Eija ; Lönnqvist, Lasse ; Leppäaho-Lakka, Jaana ; Mannonen, Laura ; Kant, Ravi ; Sironen, Tarja ; Kurkela, Satu ; Lappalainen, Maija ; Zorec, Tomaž Mark ; Zakotnik, Samo ; Vlaj, Doroteja ; Korva, Miša ; Avšič-Županc, Tatjana ; Poljak, Mario ; Smura, Teemu ; Vapalahti, Olli
• Description:
  Monkeypox virus was imported into Finland during late May-early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3-specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme-mediated evolution or co-infection.
• Subjects:
  APOBEC3-associated Mutations Finland Genomic Sequence Humans Intrahost Monkeypox Virus Genome Variation In Patient With Early Infection, Finland, 2022 Intrahost Variation Monkeypox Monkeypox Virus Mpox Mutation Outbreak Research Letter Viruses

  More +
• Source:
  Emerg Infect Dis. 2023; 29(3):649-652
• Pubmed ID:
  36703245
• Pubmed Central ID:
  PMC9973688
• Document Type:
  Journal Article
• Volume:
  29
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:7ff26c3f8c895f796d155c86b64a7e53ec152d7c3e6cdc63d998f9dac10c0278
• Download URL:
  https://stacks.cdc.gov/view/cdc/127663/cdc_127663_DS1.pdf
• File Type:
  [PDF - 1.08 MB ]