New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Heinrich, Fabian ; Huter, Tobias ; Mertens, Sophie ; Lange, Philine ; Vering, Jessica ; Heinemann, Axel ; Nörz, Dominik Sebastian ; Hoffmann, Armin ; Aepfelbacher, Martin ; Ondruschka, Benjamin ; Krasemann, Susanne ; Lütgehetmann, Marc
• Description:
  We performed autopsies on persons in Germany who died from COVID-19 and observed higher nasopharyngeal SARS-CoV-2 viral loads for variants of concern (VOC) compared with non-VOC lineages. Pulmonary inflammation and damage appeared higher in non-VOC than VOC lineages until adjusted for vaccination status, suggesting COVID-19 vaccination may mitigate pulmonary damage.
• Subjects:
  Alpha Variant Autopsy B.1.1.7 B.1.1.529 B.1.617.2 Coronavirus Coronavirus Disease COVID-19 COVID-19 Vaccines Delta Variant Germany Humans New Postmortem Perspective On Emerging SARS-CoV-2 Variants Of Concern, Germany Omicron Variant Organ Tropism Pulmonary Damage Research Letter Respiratory Infections SARS SARS-CoV-2 Severe Acute Respiratory Syndrome Coronavirus 2 Variants Of Concern Viral Load Viruses VOC Zoonoses

  More +
• Source:
  Emerg Infect Dis. 2023; 29(3):652-656
• Pubmed ID:
  36787498
• Pubmed Central ID:
  PMC9973696
• Document Type:
  Journal Article
• Volume:
  29
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:66225e6087f3dc1fee93915d3232bb789a9ddda0b66b86e743043123378286e4
• Download URL:
  https://stacks.cdc.gov/view/cdc/127657/cdc_127657_DS1.pdf
• File Type:
  [PDF - 900.73 KB ]