Efficiency of Field Laboratories for Ebola Virus Disease Outbreak during Chronic Insecurity, Eastern Democratic Republic of the Congo, 2018–2020

Mukadi-Bamuleka, Daniel; Mambu-Mbika, Fabrice; De Weggheleire, Anja; Edidi-Atani, François; Bulabula-Penge, Junior; Mfumu, Meris Matondo Kua; Legand, Anaïs; Nkuba-Ndaye, Antoine; N’kasar, Yannick Tutu Tshia; Mbala-Kingebeni, Placide; Klena, John D.; Montgomery, Joel M.; Muyembe-Tamfum, Jean-Jacques; Formenty, Pierre; van Griensven, Johan; Ariën, Kevin K.; Ahuka-Mundeke, Steve

doi:10.3201/eid2901.221025

i

Efficiency of Field Laboratories for Ebola Virus Disease Outbreak during Chronic Insecurity, Eastern Democratic Republic of the Congo, 2018–2020

Supporting Files Public Domain

1 2023
By Mukadi-Bamuleka, Daniel ; Mambu-Mbika, Fabrice ; De Weggheleire, Anja ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Mukadi-Bamuleka, Daniel ; Mambu-Mbika, Fabrice ; De Weggheleire, Anja ; Edidi-Atani, François ; Bulabula-Penge, Junior ; Mfumu, Meris Matondo Kua ; Legand, Anaïs ; Nkuba-Ndaye, Antoine ; N’kasar, Yannick Tutu Tshia ; Mbala-Kingebeni, Placide ; Klena, John D. ; Montgomery, Joel M. ; Muyembe-Tamfum, Jean-Jacques ; Formenty, Pierre ; van Griensven, Johan ; Ariën, Kevin K. ; Ahuka-Mundeke, Steve
Description:

During the 10th outbreak of Ebola virus disease in the Democratic Republic of the Congo, the Institut National de Recherche Biomédicale strategically positioned 13 decentralized field laboratories with dedicated equipment to quickly detect cases as the outbreak evolved. The laboratories were operated by national staff, who quickly handed over competencies and skills to local persons to successfully manage future outbreaks. Laboratories analyzed ≈230,000 Ebola diagnostic samples under stringent biosafety measures, documentation, and database management. Field laboratories diversified their activities (diagnosis, chemistry and hematology, survivor follow-up, and genomic sequencing) and shipped 127,993 samples from the field to a biorepository in Kinshasa under good conditions. Deploying decentralized and well-equipped laboratories run by local personnel in at-risk countries for Ebola virus disease outbreaks is an efficient response; all activities are quickly conducted in the field.
Subjects:

Disease Outbreaks Ebolavirus Hemorrhagic Fever, Ebola Humans Laboratories
Source:

Emerg Infect Dis. 2023; 29(1)
Pubmed ID:

36573642
Pubmed Central ID:

PMC9796222
Document Type:

Journal Article
Place as Subject:

Democratic Republic of the Congo
Volume:

29
Issue:

1
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:72a2fa1e316c9ed30272f8af8a33c3c6b262a767e59530a82ce88150be584b2a
Download URL:

https://stacks.cdc.gov/view/cdc/127642/cdc_127642_DS1.pdf
File Type:

[PDF - 1.53 MB ]

File Language:

English

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