Monkeypox Virus Evolution before 2022 Outbreak

Dumonteil, Eric; Herrera, Claudia; Sabino-Santos, Gilberto

doi:10.3201/eid2902.220962

i

Monkeypox Virus Evolution before 2022 Outbreak

Supporting Files Public Domain

2 2023
By Dumonteil, Eric ; Herrera, Claudia ; Sabino-Santos, Gilberto

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Dumonteil, Eric ; Herrera, Claudia ; Sabino-Santos, Gilberto
Description:

Phylogenetic analysis of monkeypox virus genomes showed statistically significant divergence and nascent subclades during the 2022 mpox outbreak. Frequency of G>A/C>T transitions has increased in recent years, probably resulting from apolipoprotein B mRNA editing enzyme catalytic polypeptide 3G (APOBEC3) deaminase editing. This microevolutionary pattern most likely reflects community spread of the virus and adaptation to humans.
Subjects:

Adaptation Disease Outbreaks Evolution Humans Monkeypox Monkeypox Virus Monkeypox Virus Evolution Before 2022 Outbreak Mpox MPXV Phylogeny Research Letter Transmission Viruses
Source:

Emerg Infect Dis. 2023; 29(2):451-453
Pubmed ID:

36692511
Pubmed Central ID:

PMC9881786
Document Type:

Journal Article
Volume:

29
Issue:

2
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:5e9a8e37f530acbe127b5acb5d997a7425ca7096a53c72e3709a4ae31268c99e
Download URL:

https://stacks.cdc.gov/view/cdc/127634/cdc_127634_DS1.pdf
File Type:

[PDF - 1.71 MB ]

File Language:

English

ON THIS PAGE

Details Supporting Files

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.