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Monkeypox Virus Evolution before 2022 Outbreak
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2 2023
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Source: Emerg Infect Dis. 2023; 29(2):451-453
[PDF-1.71 MB]
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Alternative Title:Emerg Infect Dis
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Description:Phylogenetic analysis of monkeypox virus genomes showed statistically significant divergence and nascent subclades during the 2022 mpox outbreak. Frequency of G>A/C>T transitions has increased in recent years, probably resulting from apolipoprotein B mRNA editing enzyme catalytic polypeptide 3G (APOBEC3) deaminase editing. This microevolutionary pattern most likely reflects community spread of the virus and adaptation to humans.
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Pubmed ID:36692511
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Pubmed Central ID:PMC9881786
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Document Type:
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Volume:29
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Issue:2
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