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Brainstem auditory evoked potentials in children with lead exposure
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2021
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Alternative Title:figshare Academic Research System
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Journal Article:Brazilian Journal of Otorhinolaryngology
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Corporate Authors:Department of Speech Therapy and Audiology, Faculdade de Odontologia de Bauru, Universidade de São Paulo (FOB-USP) ; Division of Field Studies and Engineering, National Institute for Occupational Safety and Health ; National Institute for Occupational Safety and Health (NIOSH) ; National Institute for Occupational Safety and Health (NIOSH), Division of Applied Research and Technology
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Description:Introduction: Earlier studies have demonstrated an auditory effect of lead exposure in children, but information on the effects of low chronic exposures needs to be further elucidated. Objective: To investigate the effect of low chronic exposures of the auditory system in children with a history of low blood lead levels, using an auditory electrophysiological test. Methods: Contemporary cross-sectional cohort. Study participants underwent tympanometry, pure tone and speech audiometry, transient evoked otoacoustic emissions, and brainstem auditory evoked potentials, with blood lead monitoring over a period of 35.5 months. The study included 130 children, with ages ranging from 18 months to 14 years, 5 months (mean age 6 years, 8 months ± 3 years, 2 months). Results: The mean time-integrated cumulative blood lead index was 12 µg/dL (SD ± 5.7, range:2.433). All participants had hearing thresholds equal to or below 20 dBHL and normal amplitudes of transient evoked otoacoustic emissions. No association was found between the absolute latencies of waves I, III, and V, the interpeak latencies I-III, III-V, and I-V, and the cumulative lead values. Conclusion: No evidence of toxic effects from chronic low lead exposures was observed on the auditory function of children living in a lead contaminated area.
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Content Notes:Stacks:34049
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Modified:03/25/2021
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Date Issued:01/01/2021
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