Update on Vaccine-Derived Poliovirus Outbreaks - Worldwide, January 2021-December 2022
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04/07/2023
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Alternative Title:Morbidity and Mortality Weekly Report (MMWR) / Vol. 72 / No. 14, April 7, 2023: Update on Vaccine-Derived Poliovirus Outbreaks - Worldwide, January 2021-December 2022
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Journal Article:Morbidity and Mortality Weekly Report (MMWR)
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Description:Circulating vaccine-derived poliovirus (cVDPV) outbreaks can occur when oral poliovirus vaccine (OPV, containing one or more Sabin-strain serotypes 1, 2, and 3) strains undergo prolonged circulation in under-vaccinated populations, resulting in genetically reverted neurovirulent virus. Following declaration of the eradication of wild poliovirus type 2 in 2015 and the global synchronized switch from trivalent OPV (tOPV, containing Sabin-strain types 1, 2, and 3) to bivalent OPV (bOPV, containing types 1 and 3 only) for routine immunization activities in April 2016, cVDPV type 2 (cVDPV2) outbreaks have been reported worldwide. This article examines the current state of vaccine-derived polio outbreaks.
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Source:Morbidity and Mortality Weekly Report (MMWR), 2023; v. 72, no. 14, p.366-371 (6 pdf pages)
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Pages in Document:p.366-371 (6 pdf pages)
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Volume:72
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Issue:14
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Main Document Checksum:urn:sha-512:05cafc3b312e80cc953fb5944e701648343bffc3c19d0d4b9952c71c183707a44dc6d2a7a2f1cdf62eb3c2c8bdb9ed7d59ababbb0c19f9d46f37fedd951a4a67
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Morbidity and Mortality Weekly Report (MMWR)