Outbreak of extensively drug-resistant Pseudomonas aeruginosa associated with artificial tears

Details

• Corporate Authors:
  Centers for Disease Control and Prevention (U.S.)
• Description:
  Distributed via the CDC Health Alert Network
  
  February 1, 2023, 7:00 PM ET
  
  CDCHAN-00485
  
  The Centers for Disease Control and Prevention (CDC) is issuing this Health Alert Network (HAN) Health Advisory about infections with an extensively drug-resistant strain of Verona Integron-mediated Metallo-β-lactamase (VIM) and Guiana-Extended Spectrum-β-Lactamase (GES)-producing carbapenem-resistant Pseudomonas aeruginosa (VIM-GES-CRPA) in 12 states. Most patients reported using artificial tears. Patients reported more than 10 different brands of artificial tears, and some patients used multiple brands. The majority of patients who used artificial tears reported using EzriCare Artificial Tears, a preservative-free, over-the-counter product packaged in multidose bottles. CDC laboratory testing identified the presence of the outbreak strain in opened EzriCare bottles with different lot numbers collected from two states. Patients and healthcare providers should immediately discontinue using EzriCare artificial tears pending additional guidance from CDC and the Food and Drug Administration (FDA).
  
  
• Subjects:
  Disease Outbreaks Drug Resistance, Microbial Lubricant Eye Drops Pseudomonas Aeruginosa Pseudomonas Infections Tears
• Source:
  HAN ; 485
• Series:
  Health Alert Network
• Document Type:
  HAN Health Advisory
• Place as Subject:
  California ; Colorado ; Connecticut ; Florida ; New Jersey ; New Mexico ; New York ; Nevada ; Texas ; Utah ; Washington ; Wisconsin
• Issue:
  485
• Collection(s):
  Health Alert Network (HAN)
• Main Document Checksum:
  urn:sha-512:bdd2fdb2388bacb6bbc0a835f43cc3f8a8bf60f6127a5b83c1b79d4ee795bd4ae26f532809392967abf87e0111c731d550098abaaefca08898694e4127b8b588
• Download URL:
  https://stacks.cdc.gov/view/cdc/124175/cdc_124175_DS1.pdf
• File Type:
  [PDF - 140.65 KB ]