Clinical and Epidemiologic Characteristics and Therapeutic Management of Patients with Vibrio Infections, Bay of Biscay, France, 2001–2019

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Hoefler, Florence ; Pouget-Abadie, Xavier ; Roncato-Saberan, Mariam ; Lemarié, Romain ; Takoudju, Eve-Marie ; Raffi, François ; Corvec, Stéphane ; Le Bras, Morgane ; Cazanave, Charles ; Lehours, Philippe ; Guimard, Thomas ; Allix-Béguec, Caroline
• Description:
  Noncholera vibriosis is a rare, opportunistic bacterial infection caused by Vibrio spp. other than V. cholerae O1/O139 and diagnosed mainly during the hot summer months in patients after seaside activities. Detailed knowledge of circulating pathogenic strains and heterogeneities in infection outcomes and disease dynamics may help in patient management. We conducted a multicenter case-series study documenting Vibrio infections in 67 patients from 8 hospitals in the Bay of Biscay, France, over a 19-year period. Infections were mainly caused by V. alginolyticus (34%), V. parahaemolyticus (30%), non-O1/O139 V. cholerae (15%), and V. vulnificus (10%). Drug-susceptibility testing revealed intermediate and resistant strains to penicillins and first-generation cephalosporins. The acute infections (e.g., those involving digestive disorder, cellulitis, osteitis, pneumonia, and endocarditis) led to a life-threatening event (septic shock), amputation, or death in 36% of patients. Physicians may need to add vibriosis to their list of infections to assess in patients with associated risk factors.
• Subjects:
  Amputation Antibacterial Agents Antimicrobial Resistance Bacterial Infections Death Humans Penicillins Vibrio Vibrio Cholerae
• Source:
  Emerg Infect Dis. 2022; 28(12):2367-2373
• Pubmed ID:
  36418019
• Pubmed Central ID:
  PMC9707594
• Document Type:
  Journal Article
• Place as Subject:
  France
• Volume:
  28
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:229c5a36e9472720b9654953c7719bdf6c9d5dfd48b4899a93261ec18f98beae
• Download URL:
  https://stacks.cdc.gov/view/cdc/123315/cdc_123315_DS1.pdf
• File Type:
  [PDF - 665.96 KB ]