Invasive Infections Caused by Lancefield Groups C/G and A Streptococcus, Western Australia, Australia, 2000–2018

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Wright, Cameron M. ; Moorin, Rachael ; Pearson, Glenn ; Dyer, John ; Carapetis, Jonathan ; Manning, Laurens
• Description:
  Epidemiologic data on invasive group C/G Streptococcus (iGCGS) infections are sparse internationally. Linked population-level hospital, pathology, and death data were used to describe the disease burden in Western Australia, Australia, during 2000-2018 compared with that of invasive group A Streptococcus (GAS, Streptococcus pyogenes) infections. Of 1,270 cases, 866 (68%) occurred in men. Patients with iGCGS infection were older (median age 62 years) than those with invasive GAS (median age 44 years; p<0.0001). The age and sex-adjusted incidence rate ratio by year was 1.08 (95% CI 1.07-1.09). The incidence rate ratio for Indigenous compared with non-Indigenous Australians was 3.6 (95% CI 3.0-4.3). The all-cause 90-day death rate was 9% for iGCGS infection compared with 7% for invasive GAS (p = 0.03). iGCGS infection was more common in men and older persons and had a higher death rate, perhaps reflecting the effect of age and comorbidities on incidence and death.
• Subjects:
  Adult Aged Aged, 80 And Over Incidence Middle Aged Streptococcal Infections Streptococcus Pyogenes Western Australia
• Source:
  Emerg Infect Dis. 2022; 28(11):2190-2197
• Pubmed ID:
  36285885
• Pubmed Central ID:
  PMC9622247
• Document Type:
  Journal Article
• Place as Subject:
  Australia
• Volume:
  28
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:6e76fe7a651cbbfa8d0490db33d9ded868f4bff8d2accb9541b2abe2160684a6
• Download URL:
  https://stacks.cdc.gov/view/cdc/122849/cdc_122849_DS1.pdf
• File Type:
  [PDF - 667.41 KB ]