Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Keyel, Alexander C. ; Russell, Alexis ; Plitnick, Jonathan ; Rowlands, Jemma V. ; Lamson, Daryl M. ; ... More +
Keyel, Alexander C. ; Russell, Alexis ; Plitnick, Jonathan ; Rowlands, Jemma V. ; Lamson, Daryl M. ; Rosenberg, Eli ; St. George, Kirsten Less -
Description:
Recently emerged SARS-CoV-2 variants have greater potential than earlier variants to cause vaccine breakthrough infections. During emergence of the Delta and Omicron variants, a matched case-control analysis used a viral genomic sequence dataset linked with demographic and vaccination information from New York, USA, to examine associations between virus lineage and patient vaccination status, patient age, vaccine type, and time since vaccination. Case-patients were persons infected with the emerging virus lineage, and controls were persons infected with any other virus lineage. Infections in fully vaccinated and boosted persons were significantly associated with the Omicron lineage. Odds of infection with Omicron relative to Delta generally decreased with increasing patient age. A similar pattern was observed with vaccination status during Delta emergence but was not significant. Vaccines offered less protection against Omicron, thereby increasing the number of potential hosts for emerging variants.
Subjects:
[+]
Antibodies, Viral COVID-19 COVID-19 Vaccines Humans SARS-COV-2 Viral Vaccines
Source:
Emerg Infect Dis. 2022; 28(10):1990-1998
Pubmed ID:
36048774
Pubmed Central ID:
PMC9514330
Document Type:
Journal Article
Place as Subject:
New York, NY
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:da630db1310467c77778b4702a787dcd28dc7c079a13dcca6423703b08ac0bae
Download URL:
https://stacks.cdc.gov/view/cdc/122503/cdc_122503_DS1.pdf
File Type:

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