Environmental Persistence of Monkeypox Virus on Surfaces in Household of Person with Travel-Associated Infection, Dallas, Texas, USA, 2021

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Morgan, Clint N. ; Whitehill, Florence ; Doty, Jeffrey B. ; Schulte, Joann ; Matheny, Audrey ; Stringer, Joey ; Delaney, Lisa J. ; Esparza, Richard ; Rao, Agam K. ; McCollum, Andrea M.
• Description:
  In July 2021, we conducted environmental sampling at the residence of a person in Dallas, Texas, USA, who had travel-associated human West African monkeypox virus (MPXV-WA). Targeted environmental swab sampling was conducted 15 days after the person who had monkeypox left the household. Results indicate extensive MPXV-WA DNA contamination, and viable virus from 7 samples was successfully isolated in cell culture. There was no statistical difference (p = 0.94) between MPXV-WA PCR positivity of porous (9/10, 90%) vs. nonporous (19/21, 90.5%) surfaces, but there was a significant difference (p<0.01) between viable virus detected in cultures of porous (6/10, 60%) vs. nonporous (1/21, 5%) surfaces. These findings indicate that porous surfaces (e.g., bedding, clothing) may pose more of a MPXV exposure risk than nonporous surfaces (e.g., metal, plastic). Viable MPXV was detected on household surfaces after at least 15 days. However, low titers (<10| PFU) indicate a limited potential for indirect transmission.
• Subjects:
  Monkeypox Virus Mpox, Monkeypox Plastics Travel Travel-Related Illness Virus Diseases
• Source:
  Emerg Infect Dis. 2022; 28(10):1982-1989
• Pubmed ID:
  35951009
• Pubmed Central ID:
  PMC9514334
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Texas ; OSHA Region 6
• CIO:
  National Center for Emerging and Zoonotic Infectious Diseases
• Topic:
  Diseases & Conditions
• Location:
  North America
• Pages in Document:
  8 pdf pages
• Volume:
  28
• Issue:
  10
• NIOSHTIC Number:
  nn:20066782
• Collection(s):
  National Institute for Occupational Safety and Health Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha-512:d05b307ee09f0a3754c84a255cf814c48a7617b30d30e255309c2217c8014af2fd98dc34a1840d4ab5d6e906c8c4a0e48b85e63b9172184cd11ea8359a23ce06
• Download URL:
  https://stacks.cdc.gov/view/cdc/122502/cdc_122502_DS1.pdf
• File Type:
  [PDF - 710.26 KB ]