Importation and Circulation of Vaccine-Derived Poliovirus Serotype 2, Senegal, 2020–2021

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Faye, Martin ; Kébé, Ousmane ; Diop, Boly ; Ndiaye, NDack ; Dosseh, Annick ; Sam, Abdoulaye ; Diallo, Aliou ; Dia, Hamet ; Diallo, Jean Pierre ; Dia, Ndongo ; Kiori, Davy Evrard ; Diop, Ousmane Madiagne ; Sall, Amadou Alpha ; Faye, Ousmane
• Description:
  Environmental surveillance for poliovirus is increasingly used in poliovirus eradication efforts as a supplement to acute flaccid paralysis (AFP) surveillance. Environmental surveillance was officially established in 2017 in Senegal, where no poliovirus had been detected since 2010. We tested sewage samples from 2 sites in Dakar monthly for polioviruses. We identified a vaccine-derived poliovirus serotype 2 on January 19, 2021, from a sample collected on December 24, 2020; by December 31, 2021, we had detected 70 vaccine-derived poliovirus serotype 2 isolates circulating in 7 of 14 regions in Senegal. Sources included 18 AFP cases, 20 direct contacts, 17 contacts in the community, and 15 sewage samples. Phylogenetic analysis revealed the circulation of 2 clusters and provided evidence on the virus introduction from Guinea. Because novel oral polio vaccine serotype 2 was used for response activities throughout Senegal, we recommend expanding environmental surveillance into other regions.
• Subjects:
  Environmental Monitoring Phylogeny Poliomyelitis Poliovirus Poliovirus Vaccine, Oral Serogroup Sewage
• Source:
  Emerg Infect Dis. 2022; 28(10):2027-2034
• Pubmed ID:
  36148906
• Pubmed Central ID:
  PMC9514370
• Document Type:
  Journal Article
• Place as Subject:
  Senegal
• Volume:
  28
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:aec6ddfc0e5ce99373a2b440bd505484ea346087a3e2a35f3ee59cc75d8a3dbc
• Download URL:
  https://stacks.cdc.gov/view/cdc/122499/cdc_122499_DS1.pdf
• File Type:
  [PDF - 2.02 MB ]