Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections

Okogbenin, Sylvanus; Erameh, Cyril; Okoeguale, Joseph; Edeawe, Osahogie; Ekuaze, Esele; Iraoyah, Kelly; Agho, John; Groger, Mirjam; Kreuels, Benno; Oestereich, Lisa; Babatunde, Femi O.; Akhideno, Peter; Günther, Stephan; Ramharter, Michael; Omansen, Till

doi:10.3201/eid2810.220625

i

Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections

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10 2022
By Okogbenin, Sylvanus ; Erameh, Cyril ; Okoeguale, Joseph ; ...

File Language:

English

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Alternative Title:

Emerg Infect Dis
Personal Author:

Okogbenin, Sylvanus ; Erameh, Cyril ; Okoeguale, Joseph ; Edeawe, Osahogie ; Ekuaze, Esele ; Iraoyah, Kelly ; Agho, John ; Groger, Mirjam ; Kreuels, Benno ; Oestereich, Lisa ; Babatunde, Femi O. ; Akhideno, Peter ; Günther, Stephan ; Ramharter, Michael ; Omansen, Till
Description:

Lassa fever is a viral hemorrhagic fever treated with supportive care and the broad-spectrum antiviral drug ribavirin. The pathophysiology, especially the role of hyperinflammation, of this disease is unknown. We report successful remission of complicated Lassa fever in 2 patients in Nigeria who received the antiinflammatory agent dexamethasone and standard ribavirin.
Subjects:

Antiviral Agents Dexamethasone Humans Lassa Fever Ribavirin
Source:

Emerg Infect Dis. 2022; 28(10):2060-2063
Pubmed ID:

36148915
Pubmed Central ID:

PMC9514364
Document Type:

Journal Article
Genre:

Dispatch
Place as Subject:

Nigeria
Volume:

28
Issue:

10
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:81cb8b9b6494d0bc77d477bcd42b2bc5707fe62e88c3cabaaafefcc047751dd1
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https://stacks.cdc.gov/view/cdc/122490/cdc_122490_DS1.pdf
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[PDF - 496.40 KB ]

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