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A Head of State Leading by Example
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10 2022
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Source: Emerg Infect Dis. 2022; 28(10):2141-2143
[PDF-2.81 MB]
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Alternative Title:Emerg Infect Dis
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Description:Timothy Ivanov (1729−1802), Inoculation of Catherine II and Her Son Paul against Smallpox (c. 1770–1800). Copper, 2.5 in/64.7 mm, 6.1 oz/173 gm. Louvre Museum, Department of Art Objects of the Middle Ages, Renaissance and Modern Times. Permalink: https://collections.louvre.fr/en/ark:/53355/cl010366995
Before the introduction of smallpox vaccine, vari- olation was practiced as a preventive measure (i.e., deliberate infection with smallpox to provide immunity), most commonly by inserting or rubbing material from smallpox lesions into the skin of un- infected persons. Most persons thus infected would get a milder case of smallpox as the virus was gener- ally introduced via the skin rather than via the re- spiratory route, as in the case of natural exposure.
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Pubmed Central ID:PMC9514359
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