Prevalence, anatomic distribution, and correlates of Chlamydia trachomatis and Neisseria gonorrhoeae infections among a cohort of men who have sex with men in Hanoi, Vietnam

Details

• Alternative Title:
  Sex Transm Dis
• Personal Author:
  Adamson, Paul C. ; Bhatia, Ramona ; Tran, Khoa D. C. ; Bui, Hao T. M. ; Vu, Diep ; Shiraishi, Ray W. ; Giang, Le Minh
• Description:
  Background:
  
  Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) disproportionately affect men who have sex with men (MSM). Data on the prevalence, anatomical distribution, and correlates of NG and CT infections among MSM in Vietnam are limited.
  
  Methods:
  
  Between July 2017 and April 2019, MSM 16 years or older, without HIV were enrolled into an observational cohort study. Baseline data, including sociodemographics, sexual behavior, and HIV status were collected. NG and CT testing were performed on urine, rectal, and pharyngeal specimens. Multivariate logistic regression models identified factors associated with NG and CT infections at baseline.
  
  Results:
  
  In total, 1489 participants underwent NG/CT testing. The median age was 22 years (IQR: 20 – 26). There were 424 (28.5%) NG or CT infections; 322 (21.6%) with CT and 173 (11.6%) with NG. Rectal infections were most common for CT (73.9%), while pharyngeal infections were most common for NG (70.5%). Independent risk factors for CT or NG infection included: ≥2 sex partners in the prior month (adjusted odds ratio [aOR] = 2.04; 95% CI: 1.44, 2.91), condomless anal sex (aOR= 1.44, 95% CI: 1.12, 1.86), and meeting sex partners online (aOR= 1.35; 95% CI: 1.03, 1.76). Recent genitourinary or rectal symptoms were not associated with infections.
  
  Conclusions:
  
  The overall and extragenital prevalence of NG and CT infections were high within this sample of young MSM without HIV in Hanoi. Testing limited to urethral specimens would have missed nearly three-quarters of CT and NG infections, supporting the need for routine testing at multiple anatomic sites.
  
  
• Subjects:
  Adult Article Chlamydia Infections Chlamydia Trachomatis Cohort Studies Gonorrhea HIV Infections Homosexuality, Male Humans Male MSM Neisseria Gonorrhoeae Pharyngeal Infections Prevalence Rectal Infections Sexual And Gender Minorities Sexual Behavior Vietnam Young Adult

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• Source:
  Sex Transm Dis. 49(7):504-510
• Pubmed ID:
  35312657
• Pubmed Central ID:
  PMC9601603
• Document Type:
  Journal Article
• Funding:
  U01 GH002150/GH/CGH CDC HHSUnited States/ ; K01 TW012170/TW/FIC NIH HHSUnited States/ ; U01GH002150/ACL/ACL HHSUnited States/ ; T32 MH080634/MH/NIMH NIH HHSUnited States/ ; L30 AI154486/AI/NIAID NIH HHSUnited States/ ; PEPFAR/PEPFARUnited States/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  49
• Issue:
  7
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:b2b7d467aced1c23b58b55c3ffe5bb1081d2e5b8c30505073da2e6c418e35a8d
• Download URL:
  https://stacks.cdc.gov/view/cdc/121972/cdc_121972_DS1.pdf
• File Type:
  [PDF - 277.76 KB ]