Effect of Nucleic Acid Amplification Testing on Population-Based Incidence Rates of Clostridium difficile Infection

Details

• Alternative Title:
  Clin Infect Dis
• Personal Author:
  Gould, Carolyn V. ; Edwards, Jonathan R. ; Cohen, Jessica ; Bamberg, Wendy M. ; Clark, Leigh Ann ; Farley, Monica M. ; Johnston, Helen ; Nadle, Joelle ; Winston, Lisa ; Gerding, Dale N. ; McDonald, L. Clifford ; Lessa, Fernanda C.
  More +
• Corporate Authors:
  Clostridium difficile Infection Surveillance Investigators, Centers for Disease Control and Prevention
• Description:
  Nucleic acid amplification testing (NAAT) is increasingly being adopted for diagnosis of Clostridium difficile infection (CDI). Data from 3 states conducting population-based CDI surveillance showed increases ranging from 43% to 67% in CDI incidence attributable to changing from toxin enzyme immunoassays to NAAT. CDI surveillance requires adjustment for testing methods.
• Subjects:
  • Clostridium Infections
  • Humans
  • Incidence
  • Molecular Diagnostic Techniques
  • Nucleic Acid Amplification Techniques
  • Sensitivity and Specificity
• Keywords:
  • Clostridium difficile
  • clinical laboratory techniques
  • nucleic acid amplification techniques
  • incidence
  • surveillance
• Source:
  Clin Infect Dis. 57(9):1304-1307
• Pubmed ID:
  23899677
• Pubmed Central ID:
  PMC9580544
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  57
• Issue:
  9
• Download URL:
  https://stacks.cdc.gov/view/cdc/121851/cdc_121851_DS1.pdf
• File Type:
  [PDF - 54.19 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:de6a383fc34d886377aa535710eae49fc0ffa01b82302cac240b66fe1f0580bb