Elizabethkingia in Children: A Comprehensive Review of Symptomatic Cases Reported from 1944–2017

Details

• Alternative Title:
  Clin Infect Dis
• Personal Author:
  Dziuban, Eric J. ; Franks, Jessica ; So, Marvin ; Peacock, Georgina ; Blaney, David D.
• Description:
  Elizabethkingia species often exhibit extensive antibiotic resistance and result in high morbidity and mortality, yet no systematic reviews exist that thoroughly characterize and quantify concerns for infected infants and children. We performed a review of literature and identified an initial 902 articles; 96 articles reporting 283 pediatric cases met our inclusion criteria and were subsequently reviewed. Case reports spanned 28 countries and ranged from 1944 to 2017. Neonatal meningitis remains the most common presentation of this organism in children, along with a range of other clinical manifestations. The majority of reported cases occurred as isolated cases, rather than within outbreaks. Mortality was high but has decreased in recent years, although neurologic sequelae among survivors remains concerning. Child outcomes can be improved through effective prevention measures and early identification and treatment of infected patients.
• Subjects:
  Child Child, Preschool Communicable Diseases, Emerging Disease Outbreaks Drug Resistance, Multiple, Bacterial Flavobacteriaceae Flavobacteriaceae Infections History, 20th Century History, 21st Century Humans Infant

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• Source:
  Clin Infect Dis. 67(1):144-149
• Pubmed ID:
  29211821
• Pubmed Central ID:
  PMC9580403
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Place as Subject:
  United States
• Volume:
  67
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:e3c900da533e524d07ee349b020766b06d4255ef7cb8202dc21beaa242444a17
• Download URL:
  https://stacks.cdc.gov/view/cdc/121850/cdc_121850_DS1.pdf
• File Type:
  [PDF - 252.65 KB ]