Pathogenesis and Transmissibility of North American Highly Pathogenic Avian Influenza A(H5N1) Virus in Ferrets

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Pulit-Penaloza, Joanna A. ; Belser, Jessica A. ; Brock, Nicole ; Thakur, Poulami Basu ; Tumpey, Terrence M. ; Maines, Taronna R.
• Description:
  Highly pathogenic avian influenza A(H5N1) viruses have spread rapidly throughout North American flyways in recent months, affecting wild birds in over 40 states. We evaluated the pathogenicity and transmissibility of a representative virus using a ferret model and examined replication kinetics of this virus in human respiratory tract cells.
• Subjects:
  Animals Birds Ferrets Humans Influenza, Human Influenza A Virus Influenza A Virus, H5N1 Subtype Influenza In Birds Orthomyxoviridae Infections/veterinary
• Source:
  Emerg Infect Dis. 2022; 28(9):1913-1915
• Pubmed ID:
  35840125
• Pubmed Central ID:
  PMC9423912
• Document Type:
  Journal Article
• Genre:
  Research Letter
• Place as Subject:
  North America
• Volume:
  28
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:a765a47e6fa1fcc2cf9d4e9befc9465c68619ebaef184be0c9225d166fd984f7
• Download URL:
  https://stacks.cdc.gov/view/cdc/121063/cdc_121063_DS1.pdf
• File Type:
  [PDF - 915.95 KB ]