Ethnic disparities in early-onset gastric cancer: a population-based study in Texas and California

Details

• Alternative Title:
  Cancer Epidemiol Biomarkers Prev
• Personal Author:
  Tavakkoli, Anna ; Pruitt, Sandi L ; Hoang, Anh Q. ; Zhu, Hong ; Hughes, Amy E ; McKey, Thomas A. ; Elmunzer, B. Joseph ; Kwon, Richard S. ; Murphy, Caitlin C. ; Singal, Amit G.
• Description:
  Background:
  
  Incidence rates of gastric cancer are increasing in young adults (age <50 years), particularly among Hispanic persons. We estimated incidence rates of early-onset gastric cancer (EOGC) among Hispanic and non-Hispanic White persons by census tract poverty level and county-level metro/non-metro residence.
  
  Methods:
  
  We used population-based data from the California and Texas Cancer Registries from 1995–2016 to estimate age-adjusted incidence rates of EOGC among Hispanic and non-Hispanic White persons by year, sex, tumor stage, census tract poverty level, metro vs. non-metro county, and state. We used logistic regression models to identify factors associated with distant stage diagnosis.
  
  Results:
  
  Of 3047 persons diagnosed with EOGC, 73.2% were Hispanic White. Incidence rates were 1.29 (95% CI 1.24, 1.35) and 0.31 (95% CI 0.29, 0.33) per 100,000 Hispanic White and non-Hispanic White persons, respectively, with consistently higher incidence rates among Hispanic persons at all levels of poverty. There was no statistically significant associations between ethnicity and distant stage diagnosis in adjusted analysis.
  
  Conclusion:
  
  There are ethnic disparities in EOGC incidence rates that persist across poverty levels.
  
  Impact:
  
  EOGC incidence rates vary by ethnicity and poverty; these factors should be considered when assessing disease risk and targeting prevention efforts.
  
  
• Subjects:
  Ethnicity Humans Incidence Middle Aged Stomach Neoplasms White People Young Adult
• Source:
  Cancer Epidemiol Biomarkers Prev. 31(9):1710-1719
• Pubmed ID:
  35732290
• Pubmed Central ID:
  PMC9444918
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Place as Subject:
  California ; Texas
• Volume:
  31
• Issue:
  9
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:6df000a22d2621f89a07ffaee6c4c7bf7b13cf5b7ea531705c0d7c5a0ae428e1
• Download URL:
  https://stacks.cdc.gov/view/cdc/120922/cdc_120922_DS1.pdf
• File Type:
  [PDF - 434.06 KB ]