Occupational Exposure to Talc Containing Asbestos

Details

• Journal Article:
  National Institute for Occupational Safety and Health
• Personal Author:
  Dement, John M. ; Zumwalde, Ralph D. ; Gamble, John F. ; Fellner, William ; DeMeo, Michael J. ; Brown, David P. ; Wagoner, Joseph K.
• Description:
  Mortality and morbidity patterns were studied among White male talc (14807966) millers and miners in upper New York state. The mortality study included 398 miners who began employment between 1947 and 1960. There was a significant increase in mortality due to bronchogenic cancer, nonmalignant respiratory disease excluding influenza and pneumonia, and respiratory tuberculosis. The average latency period for bronchogenic cancer was 20 years. The morbidity study included 156 current miners. Among those with more than 15 years of exposure, there was an increased prevalence of pleural thickening, reduced forced expiratory volume in 1 second, decreased forced vital capacity, and lower air flow rates. Talc samples from the mines were analyzed, and most contained tremolite (60649538), anthophyllite (17068789), chrysotile (12001295), antigorite (61076980), and lizardite (61026899), and traces of dolomite (16389881), calcite (13397267), and quartz (14808607). Time weighted average exposures to asbestiform amphiboles were in excess of present OSHA standards in many mine and mill operations, and more than 90 percent of the total airborne fibers were less than 5 microns in length. The authors conclude that exposures to the these talcs are associated with an increased risk of pleural thickening, pleural calcification, bronchogenic cancer, and nonmalignant respiratory disease. [Description provided by NIOSH]
• Content Notes:
  I. Environmental Study / John M. Dement, Ralph D. Zumwalde -- I I. Cross Sectional Morbidity Study / John F. Gamble, William Fellner, Michael J. DeMeo -- Ill. Retrospective Cohort Study of Mortality /David P. Brown, Joseph K. Wagoner.
• Subjects:
  Asbestos Carcinogens Inorganic Chemicals Mining Mortality Occupational Health Respiratory Tract Diseases Safety
• Keywords:
  NIOSH-Author; Mining; Miners; Asbestos-dusts; Data-collection; Data-analysis; Mortality-data; Carcinogenesis; Respiratory-system-disorders; Latent-period
• Source:
  Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 80-115, 1980 Feb; :1-118
• Series:
  NIOSH Numbered Publications
• DOI:
  https://doi.org/10.26616/NIOSHPUB80115
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Technical Report
• Place as Subject:
  New York ; Ohio ; OSHA Region 2 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  120 pdf pages
• NIOSHTIC Number:
  nn:00095012
• NTIS Accession Number:
  PB80-193352
• CAS Registry Number:
  Anthophyllite (CAS RN 17068-78-9) ; Antigorite ((Mg0.5-1Fe0-0.5)3Si2(OH)4O5) (CAS RN 61076-98-0) ; Calcite (CAS RN 13397-26-7) ; Chrysotile (CAS RN 12001-29-5) ; Dolomite (CaMg(CO3)2) (CAS RN 16389-88-1) ; Ferrolizardite (CAS RN 12415-67-7) ; Quartz (SiO2) (CAS RN 14808-60-7) ; Talc (Mg3H2(SiO3)4) (CAS RN 14807-96-6) ; Tremolite (Ca2[(Mg0.9-1Fe0-0.1)4.5-5Al0-0.5](Si7.5-8Al0-0.5)(OH)2O22) (CAS RN 14567-73-8)
• Federal Fiscal Year:
  1980
• Peer Reviewed:
  False
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:0c9cd508b0aab128a5802f21b2632ea72df479499ede65fd976ae68ae8ae501658d47d183a8baf6ef9fef418e12196b72c327e12843800527455535834dec3ac
• Download URL:
  https://stacks.cdc.gov/view/cdc/120219/cdc_120219_DS1.pdf
• File Type:
  [PDF - 5.25 MB ]