Flavoring-Related Lung Disease: Information for Healthcare Providers

Details

• Journal Article:
  National Institute for Occupational Safety and Health
• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  Severe obstructive lung disease has been identified in people who work with flavoring chemicals containing diacetyl, including butter flavoring. Animal studies suggest that some flavoring chemicals similar to diacetyl, such as 2,3-pentanedione, may also be a hazard. Cases of severe lung disease have occurred in microwave popcorn plants and flavoring production plants. Lung biopsies in some affected people have shown the presence of a rare condition; constrictive bronchiolitis obliterans (also referred to as constrictive bronchiolitis, obliterative bronchiolitis, and bronchiolitis obliterans). In some workers, fixed airways obstruction has been severe enough to be fatal. Description provided by NIOSH
• Content Notes:
  221274 ; Includes bibliographical references (p. 11-12).
• Subjects:
  • Air Pollutants, Occupational
  • Chemistry
  • Diacetyl
  • Fibrosis
  • Hypersensitivity
  • Lung
  • Lung Diseases
  • Occupational Diseases
  • Occupational Exposure
  • Occupational Health
  More +
• Keywords:
  • Lung; Lung-disease; Lung-disorders; Lung-function; Lung-irritants; Lung-tissue; Chemical-hypersensitivity; Chemical-properties; Humans; Men; Women; Exposure-limits; Exposure-levels; Workers; Respiratory-system-disorders; Pulmonary-system-disorders; Pulmonary-disorders; Fibrogenicity; Fibrosis
• Source:
  Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2012-148, 2012 May; :1-6
• Series:
  NIOSH Numbered Publications
• Document Type:
  Text
• Genre:
  Handout/Flyer
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  EID - Education and Information Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  2 pdf pages
• NIOSHTIC Number:
  nn:20040973
• CAS Registry Number:
  • Butanedione (CAS RN 431-03-8)
• Federal Fiscal Year:
  2012
• Peer Reviewed:
  False
• Download URL:
  https://stacks.cdc.gov/view/cdc/11910/cdc_11910_DS1.pdf
• File Type:
  [PDF - 1.92 MB]
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b77e0754c589b67355cfba5ba4db4ccfdc21b3f69c6d5e3d6528642fe392e15f4a7fe1d9b229251a0a6aa6518cbd6d99661d1a20105157cc28db5638245cf162