Peri-Pregnancy Cannabis Use and Autism Spectrum Disorder in the Offspring: Findings from the Study to Explore Early Development

Details

• Alternative Title:
  J Autism Dev Disord
• Personal Author:
  DiGuiseppi, Carolyn ; Crume, Tessa ; Van Dyke, Julia ; Sabourin, Katherine R. ; Soke, Gnakub N. ; Croen, Lisa A. ; Daniels, Julie L. ; Lee, Li-Ching ; Schieve, Laura A. ; Windham, Gayle C. ; Friedman, Sandra ; Rosenberg, Cordelia Robinson
• Description:
  The association of autism spectrum disorder (ASD) with self-reported maternal cannabis use from 3 months pre-conception to delivery ("peri-pregnancy") was assessed in children aged 30-68 months, born 2003 to 2011. Children with ASD (N = 1428) were compared to children with other developmental delays/disorders (DD, N = 1198) and population controls (POP, N = 1628). Peri-pregnancy cannabis use was reported for 5.2% of ASD, 3.2% of DD and 4.4% of POP children. Adjusted odds of peri-pregnancy cannabis use did not differ significantly between ASD cases and DD or POP controls. Results were similar for any use during pregnancy. However, given potential risks suggested by underlying neurobiology and animal models, further studies in more recent cohorts, in which cannabis use and perception may have changed, are needed.
• Keywords:
  Autism Spectrum Disorder Cannabis Case-Control Studies Epidemiology Female Humans Marijuana Pregnancy
• Source:
  J Autism Dev Disord. 52(11):5064-5071
• Pubmed ID:
  34767135
• Pubmed Central ID:
  PMC9112286
• Document Type:
  Journal Article
• Funding:
  U10DD000184/CC/CDC HHSUnited States/ ; U10DD000182/CC/CDC HHSUnited States/ ; U10DD000498/CC/CDC HHSUnited States/ ; U10 DD000181/DD/NCBDD CDC HHSUnited States/ ; U10 DD000184/DD/NCBDD CDC HHSUnited States/ ; U10DD000180/CC/CDC HHSUnited States/ ; U10DDD0183/CC/CDC HHSUnited States/ ; U10 DD000182/DD/NCBDD CDC HHSUnited States/ ; U01 DD001290/DD/NCBDD CDC HHSUnited States/ ; U10 DD000183/DD/NCBDD CDC HHSUnited States/ ; P30 ES010126/ES/NIEHS NIH HHSUnited States/ ; U10 DD000180/DD/NCBDD CDC HHSUnited States/ ; U01 DD001210/DD/NCBDD CDC HHSUnited States/ ; U01 DD000498/DD/NCBDD CDC HHSUnited States/ ; U10DD000181/CC/CDC HHSUnited States/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  52
• Issue:
  11
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:30c9a2af4da87e8c0394dba4b9d4ef56a3e9cfeab85623f77e07e41fbf5f108b
• Download URL:
  https://stacks.cdc.gov/view/cdc/117629/cdc_117629_DS1.pdf
• File Type:
  [PDF - 83.26 KB ]