Invasive Group A Streptococcus Outbreaks Associated with Home Healthcare, England, 2018–2019

Nabarro, Laura E.; Brown, Colin S.; Balasegaram, Sooria; Decraene, Valérie; Elston, James; Kapadia, Smita; Harrington, Pauline; Hoffman, Peter; Mearkle, Rachel; Patel, Bharat; Ready, Derren; Robinson, Esther; Lamagni, Theresa

doi:10.3201/eid2805.211497

i

Invasive Group A Streptococcus Outbreaks Associated with Home Healthcare, England, 2018–2019

Supporting Files Public Domain

5 2022
By Nabarro, Laura E. ; Brown, Colin S. ; Balasegaram, Sooria ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Nabarro, Laura E. ; Brown, Colin S. ; Balasegaram, Sooria ; Decraene, Valérie ; Elston, James ; Kapadia, Smita ; Harrington, Pauline ; Hoffman, Peter ; Mearkle, Rachel ; Patel, Bharat ; Ready, Derren ; Robinson, Esther ; Lamagni, Theresa
Description:

Healthcare-associated invasive group A Streptococcus (iGAS) outbreaks are common worldwide, but only England has reported outbreaks associated with home healthcare (HHC). We describe 10 outbreaks during 2018-2019 in England. A total of 96 iGAS cases (range 2-39 per outbreak) and 28 deaths (case-fatality rate 29%) occurred. Outbreak duration ranged from 3-517 days; median time between sequential cases was 20.5 days (range 1-225 days). Outbreak identification was difficult, but emm typing and whole-genome sequencing improved detection. Network analyses indicated multiple potential transmission routes. Screening of 366 HHC workers from 9 outbreaks identified group A Streptococcus carriage in just 1 worker. Outbreak control required multiple interventions, including improved infection control, equipment decontamination, and antimicrobial prophylaxis for staff. Transmission routes and effective interventions are not yet clear, and iGAS outbreaks likely are underrecognized. To improve patient safety and reduce deaths, public health agencies should be aware of HHC-associated iGAS.
Subjects:

Cross Infection Delivery Of Health Care Disease Outbreaks Humans Streptococcal Infections
Source:

Emerg Infect Dis. 2022; 28(5):915-923
Pubmed ID:

35451366
Pubmed Central ID:

PMC9045425
Document Type:

Journal Article
Place as Subject:

England
Volume:

28
Issue:

5
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:77151ed98afd83966de44975d07462f7109678866d1858323462ff6fa9ee9f1e
Download URL:

https://stacks.cdc.gov/view/cdc/117276/cdc_117276_DS1.pdf
File Type:

[PDF - 854.17 KB ]

File Language:

English

ON THIS PAGE

Details Supporting Files

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.