Impact of Rotavirus Vaccination on Rotavirus Hospitalizations in Taiwanese Children

Burke, Rachel M.; Shih, Shuman; Hsiung, Chao Agnes; Yen, Catherine; Jiang, Baoming; Parashar, Umesh D.; Tate, Jacqueline E.; Wu, Fang-Tzy; Huang, Yhu-Chering

doi:10.1016/j.vaccine.2021.10.064

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Impact of Rotavirus Vaccination on Rotavirus Hospitalizations in Taiwanese Children

12 03 2021
By Burke, Rachel M. ; Shih, Shuman ; Hsiung, Chao Agnes ; ...
http://dx.doi.org/10.1016/j.vaccine.2021.10.064
Source: Vaccine. 39(49):7135-7139

[PDF-511.89 KB]

English

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Details:

Alternative Title:

Vaccine
Personal Author:

Burke, Rachel M. ; Shih, Shuman ; Hsiung, Chao Agnes ; Yen, Catherine ; Jiang, Baoming ; ... More +

Burke, Rachel M. ; Shih, Shuman ; Hsiung, Chao Agnes ; Yen, Catherine ; Jiang, Baoming ; Parashar, Umesh D. ; Tate, Jacqueline E. ; Wu, Fang-Tzy ; Huang, Yhu-Chering Less -
Description:

In 2006, two rotavirus vaccines were licensed in Taiwan but were not added to the national immunization schedule. National Health Insurance data from 2003 through 2017 were used to compare rotavirus-associated pediatric hospitalizations before and after vaccine introduction. Rotavirus hospitalization rates among children < 5 years of age significantly declined by 24% (95% confidence interval [CI] 23 - 25%) in post-vaccine compared to pre-vaccine rotavirus seasons. Rotavirus hospitalization rates declined by 42% (95% CI 39 - 44%) among infants < 12 months of age, and by 38% (95% CI 36 - 40%) among children 12 - 23 months of age. These findings suggest that, despite not being included in the national immunization schedule, rotavirus vaccines had a measurable impact on reducing rotavirus hospitalization burden among Taiwanese children.
Subjects:

[+]

Child Gastroenteritis Hospitalization Humans Infant Rotavirus Rotavirus Infections Rotavirus Vaccines Vaccination
Source:

Vaccine. 39(49):7135-7139
Pubmed ID:

34785101
Pubmed Central ID:

PMC9014808
Document Type:

Journal Article
Funding:

CC999999/ImCDC/Intramural CDC HHSUnited States/
Volume:

39
Issue:

49
Collection(s):

CDC Public Access
Main Document Checksum:

[+]

urn:sha256:67c39e1616311b966bfba6b9e19a204e246e256e7ad6f8791d456e68fbf6f845
Download URL:

https://stacks.cdc.gov/view/cdc/116488/cdc_116488_DS1.pdf
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	nihms-1791638-f0001.jpg	jpeg
	nihms-1791638.nxml	xml
	NIHMS1791638-supplement-Supplemental_material.docx	docx

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