Impact of Rotavirus Vaccination on Rotavirus Hospitalizations in Taiwanese Children

Details

• Alternative Title:
  Vaccine
• Personal Author:
  Burke, Rachel M. ; Shih, Shuman ; Hsiung, Chao Agnes ; Yen, Catherine ; Jiang, Baoming ; Parashar, Umesh D. ; Tate, Jacqueline E. ; Wu, Fang-Tzy ; Huang, Yhu-Chering
• Description:
  In 2006, two rotavirus vaccines were licensed in Taiwan but were not added to the national immunization schedule. National Health Insurance data from 2003 through 2017 were used to compare rotavirus-associated pediatric hospitalizations before and after vaccine introduction. Rotavirus hospitalization rates among children < 5 years of age significantly declined by 24% (95% confidence interval [CI] 23 - 25%) in post-vaccine compared to pre-vaccine rotavirus seasons. Rotavirus hospitalization rates declined by 42% (95% CI 39 - 44%) among infants < 12 months of age, and by 38% (95% CI 36 - 40%) among children 12 - 23 months of age. These findings suggest that, despite not being included in the national immunization schedule, rotavirus vaccines had a measurable impact on reducing rotavirus hospitalization burden among Taiwanese children.
• Subjects:
  Child Gastroenteritis Hospitalization Humans Infant Rotavirus Rotavirus Infections Rotavirus Vaccines Vaccination
• Source:
  Vaccine. 39(49):7135-7139
• Pubmed ID:
  34785101
• Pubmed Central ID:
  PMC9014808
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  39
• Issue:
  49
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:67c39e1616311b966bfba6b9e19a204e246e256e7ad6f8791d456e68fbf6f845
• Download URL:
  https://stacks.cdc.gov/view/cdc/116488/cdc_116488_DS1.pdf
• File Type:
  [PDF - 511.89 KB ]