Economic burden of influenza illness among children under 5 years in Suzhou, China: Report from the cost surveys during 2011/12 to 2016/17 influenza seasons

Details

• Alternative Title:
  Vaccine
• Personal Author:
  Wang, Yin ; Chen, Liling ; Cheng, Fangfang ; Biggerstaff, Matthew ; Situ, Sujian ; Zhou, Suizan ; Gao, Junmei ; Liu, Changpeng ; Zhang, Jun ; Millman, Alexander J. ; Zhang, Tao ; Tian, Jianmei ; Zhao, Genming
• Description:
  Background:
  
  Data are limited on the economic burden of seasonal influenza in China. We estimated the cost due to influenza illness among children < 5-year-old in Suzhou, China.
  
  Methods:
  
  This study adopted a societal perspective to estimate direct medical cost, direct non-medical cost, and indirect cost related to lost productivity. Data to calculate costs and rates of three influenza illness outcomes (non-medically attended, outpatient and hospitalization) were collected from prospective community-based cohort studies and hospital-based enhanced laboratory-confirmed influenza surveillance in Suzhou during the 2011/12 to 2016/17 influenza seasons. We used mean cost-per-episode, annual incidence rates of episodes of each outcome, and annual population size to estimate the total annual economic burden of influenza illnesses among children < 5-year-old for Suzhou. All costs were reported in 2017 U.S. dollars.
  
  Results:
  
  The mean cost-per-episode (standard deviation) was $9.92 (13.26) for non-medically attended influenza, $161.05 (176.98) for influenza outpatient illnesses, and $1425.95 (603.59) for influenza hospitalizations. By applying the annual incidence rates to the population size, we estimated an annual total of 4,919 episodes of non-medically attended influenza, 21,994 influenza outpatient, and 2,633 influenza hospitalization. Total annual economic burden of influenza to society among children < 5-year-old in Suzhou was $7.37 (95% confidence interval, 6.9–7.8) million, with estimated costs for non-medically attended influenza of $49,000 (46,000–52,000), influenza outpatients $3.5 (3.3–3.8) million, and influenza hospitalizations $3.8 (3.6–3.9) million. Among outpatients, the indirect cost was 36.3% ($1.3 million) of total economic burden, accounting for 21,994 days of lost productivity annually. Among inpatients, the indirect cost was 22.1% ($829,000), accounting for 18,431 days of lost productivity annually.
  
  Conclusions:
  
  Our findings show that influenza in children < 5-year-oldcauses substantial societal economic burden in Suzhou, China. Assessing the potential economic benefit of increasing influenza vaccination coverage in this population is warranted.
  
  
• Subjects:
  Child Child, Preschool Cost Of Illness Hospitalization Humans Influenza, Human Prospective Studies Seasons
• Source:
  Vaccine. 39(8):1303-1309
• Pubmed ID:
  33494968
• Pubmed Central ID:
  PMC9008708
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/ ; U2G GH000018/GH/CGH CDC HHSUnited States/
• Place as Subject:
  China
• Volume:
  39
• Issue:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:6c509658b5b9122f303d7ff49d4a322447780df7b6b22428c96549e6c0e60740
• Download URL:
  https://stacks.cdc.gov/view/cdc/116466/cdc_116466_DS1.pdf
• File Type:
  [PDF - 107.95 KB ]