Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers

Laing, Eric D.; Weiss, Carol D.; Samuels, Emily C.; Coggins, Si’Ana A.; Wang, Wei; Wang, Richard; Vassell, Russell; Sterling, Spencer L.; Tso, Marana S.; Conner, Tonia; Goguet, Emilie; Moser, Matthew; Jackson-Thompson, Belinda M.; Illinik, Luca; Davies, Julian; Ortega, Orlando; Parmelee, Edward; Hollis-Perry, Monique; Maiolatesi, Santina E.; Wang, Gregory; Ramsey, Kathleen F.; Reyes, Anatalio E.; Alcorta, Yolanda; Wong, Mimi A.; Lindrose, Alyssa R.; Duplessis, Christopher A.; Tribble, David R.; Malloy, Allison M.W.; Burgess, Timothy H.; Pollett, Simon D.; Olsen, Cara H.; Broder, Christopher C.; Mitre, Edward

doi:10.3201/eid2804.212037

i

Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers

Supporting Files

4 2022
By Laing, Eric D. ; Weiss, Carol D. ; Samuels, Emily C. ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Laing, Eric D. ; Weiss, Carol D. ; Samuels, Emily C. ; Coggins, Si’Ana A. ; Wang, Wei ; Wang, Richard ; Vassell, Russell ; Sterling, Spencer L. ; Tso, Marana S. ; Conner, Tonia ; Goguet, Emilie ; Moser, Matthew ; Jackson-Thompson, Belinda M. ; Illinik, Luca ; Davies, Julian ; Ortega, Orlando ; Parmelee, Edward ; Hollis-Perry, Monique ; Maiolatesi, Santina E. ; Wang, Gregory ; Ramsey, Kathleen F. ; Reyes, Anatalio E. ; Alcorta, Yolanda ; Wong, Mimi A. ; Lindrose, Alyssa R. ; Duplessis, Christopher A. ; Tribble, David R. ; Malloy, Allison M.W. ; Burgess, Timothy H. ; Pollett, Simon D. ; Olsen, Cara H. ; Broder, Christopher C. ; Mitre, Edward ; Laing, Eric D. ; Weiss, Carol D. ; Samuels, Emily C. ; Coggins, Si’Ana A. ; Wang, Wei ; Wang, Richard ; Vassell, Russell ; Sterling, Spencer L. ; Tso, Marana S. ; Conner, Tonia ; Goguet, Emilie ; Moser, Matthew ; Jackson-Thompson, Belinda M. ; Illinik, Luca ; Davies, Julian ; Ortega, Orlando ; Parmelee, Edward ; Hollis-Perry, Monique ; Maiolatesi, Santina E. ; Wang, Gregory ; Ramsey, Kathleen F. ; Reyes, Anatalio E. ; Alcorta, Yolanda ; Wong, Mimi A. ; Lindrose, Alyssa R. ; Duplessis, Christopher A. ; Tribble, David R. ; Malloy, Allison M.W. ; Burgess, Timothy H. ; Pollett, Simon D. ; Olsen, Cara H. ; Broder, Christopher C. ; Mitre, Edward
Description:

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies decay but persist 6 months postvaccination; lower levels of neutralizing titers persist against Delta than wild-type virus. Of 227 vaccinated healthcare workers tested, only 2 experienced outpatient symptomatic breakthrough infections, despite 59/227 exhibiting serologic evidence of SARS-CoV-2 infection, defined as presence of nucleocapsid protein antibodies.
Subjects:

Antibodies, Viral Antibody Formation Covid-19 Covid-19 Vaccines Health Personnel Humans Sars-Cov-2 Vaccination
Source:

Emerg Infect Dis. 2022; 28(4):828-832 ; Emerg Infect Dis. 2022; 28(4):828-832
Pubmed ID:

35203111
Pubmed Central ID:

PMC8962883
Document Type:

Journal Article
Funding:

Y01 AI005072/AI/NIAID NIH HHSUnited States/
Place as Subject:

United States
Volume:

28
Issue:

4
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:da7a7b4fa9e5ab80925dee7cdfbc85665374ff2ea747844f51721f31e7c22b49
Download URL:

https://stacks.cdc.gov/view/cdc/116335/cdc_116335_DS1.pdf
File Type:

[PDF - 1.06 MB ]

File Language:

English

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