Sensitivity of Mycobacterium leprae to Telacebec

Lahiri, Ramanuj; Adams, Linda B.; Thomas, Sangeeta Susan; Pethe, Kevin

doi:10.3201/eid2803.210394

i

Sensitivity of Mycobacterium leprae to Telacebec

Supporting Files Public Domain

3 2022
By Lahiri, Ramanuj ; Adams, Linda B. ; Thomas, Sangeeta Susan ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Lahiri, Ramanuj ; Adams, Linda B. ; Thomas, Sangeeta Susan ; Pethe, Kevin
Description:

The treatment of leprosy is long and complex, benefiting from the development of sterilizing, rapidly-acting drugs. Reductive evolution made Mycobacterium leprae exquisitely sensitive to Telacebec, a phase 2 drug candidate for tuberculosis| The unprecedented potency of Telacebec against M. leprae warrants further validation in clinical trials.
Subjects:

Imidazoles Mycobacterium Leprae Piperidines Pyridines
Source:

Emerg Infect Dis. 2022; 28(3):749-751
Pubmed ID:

35202539
Pubmed Central ID:

PMC8888226
Document Type:

Journal Article
Genre:

Letter
Volume:

28
Issue:

3
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:711100d117e45f0b37d0e1358cf6477b7ebda472ed76e0a2405715518af1095b
Download URL:

https://stacks.cdc.gov/view/cdc/115199/cdc_115199_DS1.pdf
File Type:

[PDF - 1.05 MB ]

File Language:

English

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