Sensitivity of Mycobacterium leprae to Telacebec

Lahiri, Ramanuj; Adams, Linda B.; Thomas, Sangeeta Susan; Pethe, Kevin

doi:10.3201/eid2803.210394

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Sensitivity of Mycobacterium leprae to Telacebec

3 2022
By Lahiri, Ramanuj ; Adams, Linda B. ; Thomas, Sangeeta Susan ; ...
http://dx.doi.org/10.3201/eid2803.210394
Source: Emerg Infect Dis. 2022; 28(3):749-751

[PDF-1.05 MB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Lahiri, Ramanuj ; Adams, Linda B. ; Thomas, Sangeeta Susan ; Pethe, Kevin

Lahiri, Ramanuj ; Adams, Linda B. ; Thomas, Sangeeta Susan ; Pethe, Kevin Less -
Description:

The treatment of leprosy is long and complex, benefiting from the development of sterilizing, rapidly-acting drugs. Reductive evolution made Mycobacterium leprae exquisitely sensitive to Telacebec, a phase 2 drug candidate for tuberculosis| The unprecedented potency of Telacebec against M. leprae warrants further validation in clinical trials.
Subjects:

[+]

Imidazoles Mycobacterium Leprae Piperidines Pyridines
Source:

Emerg Infect Dis. 2022; 28(3):749-751
Pubmed ID:

35202539
Pubmed Central ID:

PMC8888226
Document Type:

Journal Article
Genre:

Letter
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:711100d117e45f0b37d0e1358cf6477b7ebda472ed76e0a2405715518af1095b
Download URL:

https://stacks.cdc.gov/view/cdc/115199/cdc_115199_DS1.pdf
File Type:

	21-0394-F.gif	gif
	21-0394-F.jpg	jpeg
	21-0394.nxml	xml

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