Infection Control Measures and Prevalence of SARS-CoV-2 IgG among 4,554 University Hospital Employees, Munich, Germany

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Erber, Johanna ; Kappler, Verena ; Haller, Bernhard ; Mijočević, Hrvoje ; Galhoz, Ana ; Prazeres da Costa, Clarissa ; Gebhardt, Friedemann ; Graf, Natalia ; Hoffmann, Dieter ; Thaler, Markus ; Lorenz, Elke ; Roggendorf, Hedwig ; Kohlmayer, Florian ; Henkel, Andreas ; Menden, Michael P. ; Ruland, Jürgen ; Spinner, Christoph D. ; Protzer, Ulrike ; Knolle, Percy ; Lingor, Paul
• Corporate Authors:
  on behalf of the SeCoMRI Study Group2
• Description:
  Hospital staff are at high risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during the coronavirus disease (COVID-19) pandemic. This cross-sectional study aimed to determine the prevalence of SARS-CoV-2 infection in hospital staff at the University Hospital rechts der Isar in Munich, Germany, and identify modulating factors. Overall seroprevalence of SARS-CoV-2-IgG in 4,554 participants was 2.4%. Staff engaged in direct patient care, including those working in COVID-19 units, had a similar probability of being seropositive as non-patient-facing staff. Increased probability of infection was observed in staff reporting interactions with SARS-CoV-2‒infected coworkers or private contacts or exposure to COVID-19 patients without appropriate personal protective equipment. Analysis of spatiotemporal trajectories identified that distinct hotspots for SARS-CoV-2‒positive staff and patients only partially overlap. Patient-facing work in a healthcare facility during the SARS-CoV-2 pandemic might be safe as long as adequate personal protective equipment is used and infection prevention practices are followed inside and outside the hospital.
• Subjects:
  Cross-Sectional Studies Health Personnel Hospitals, University Humans Immunoglobulin G Infection Control Personnel, Hospital Prevalence Seroepidemiologic Studies
• Source:
  Emerg Infect Dis. 2022; 28(3):572-581
• Pubmed ID:
  35195515
• Pubmed Central ID:
  PMC8888242
• Document Type:
  Journal Article
• Place as Subject:
  Germany
• Volume:
  28
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:bd2090ee6aa4dc7437c25b2bff4fd595d040011d78a830f37f8658d09a4b11d6
• Download URL:
  https://stacks.cdc.gov/view/cdc/115196/cdc_115196_DS1.pdf
• File Type:
  [PDF - 2.98 MB ]