Role of Anopheles Mosquitoes in Cache Valley Virus Lineage Displacement, New York, USA

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Dieme, Constentin ; Ngo, Kiet A. ; Tyler, Shaun ; Maffei, Joseph G. ; Zink, Steven D. ; Dupuis, Alan P. ; Koetzner, Cheri A. ; Shultis, Chelsea ; Stout, Jessica ; Payne, Anne F. ; Backenson, P. Bryon ; Kuo, Lili ; Drebot, Michael A. ; Ciota, Alexander T. ; Kramer, Laura D.
• Description:
  Cache Valley virus (CVV) is a mosquitoborne virus that infects livestock and humans. We report results of surveillance for CVV in New York, USA, during 2000-2016; full-genome analysis of selected CVV isolates from sheep, horse, humans, and mosquitoes from New York and Canada; and phenotypic characterization of selected strains. We calculated infection rates by using the maximum-likelihood estimation method by year, region, month, and mosquito species. The highest maximum-likelihood estimations were for Anopheles spp. mosquitoes. Our phylogenetic analysis identified 2 lineages and found evidence of segment reassortment. Furthermore, our data suggest displacement of CVV lineage 1 by lineage 2 in New York and Canada. Finally, we showed increased vector competence of An. quadrimaculatus mosquitoes for lineage 2 strains of CVV compared with lineage 1 strains.
• Subjects:
  Animals Anopheles Bunyamwera Virus Horses Mosquito Vectors Phylogeny Sheep
• Source:
  Emerg Infect Dis. 2022; 28(2):303-313
• Document Type:
  Journal Article
• Place as Subject:
  New York
• Volume:
  28
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha-512:1db7f0404f00d7ebbc2c87fd6c11fd3fcc2f389a513e1bb58c2f4a3e476d983c190c9da9fe40bcc4e089b0a1ff12bcbbd4f1df01050a11e3596439daef32a64e
• Download URL:
  https://stacks.cdc.gov/view/cdc/114521/cdc_114521_DS1.pdf
• File Type:
  [PDF - 1.69 MB ]