Effectiveness of Maternal Vaccination with MRNA COVID-19 Vaccine During Pregnancy Against COVID-19–associated Hospitalization in Infants Aged <6 Months — 17 States, July 2021–January 2022

Details

• Personal Author:
  Halasa, Natasha B. ; Olson, Samantha M. ; Staat, Mary A. ; Newhams, Margaret M. ; Price, Ashley M. ; Boom, Julie A. ; Sahni, Leila C. ; Cameron, Melissa A. ; Pannaraj, Pia S. ; Bline, Katherine E. ; Bhumbra, Samina S. ; Bradford, Tamara T. ; Chiotos, Kathleen ; Coates, Bria M. ; Cullimore, Melissa L. ; Cvijanovich, Natalie Z. ; Flori, Heidi R. ; Gertz, Shira J. ; Heidemann, Sabrina M. ; Hobbs, Charlotte V. ; Hume, Janet R. ; Irby, Katherine ; Kamidani, Satoshi ; Kong, Michele ; Levy, Emily R. ; Mack, Elizabeth H. ; Maddux, Aline B. ; Michelson, Kelly N. ; Nofziger, Ryan A. ; Schuster, Jennifer E. ; Schwartz, Stephanie P. ; Smallcomb, Laura ; Tarquinio, Keiko M. ; Walker, Tracie C. ; Zinter, Matt S. ; Gilboa, Suzanne M. ; Polen, Kara N. ; Campbell, Angela P. ; Randolph, Adrienne G. ; Patel, Manish M.
• Corporate Authors:
  Overcoming COVID-19 Investigators ; CDC COVID-19 Emergency Response Team
• Description:
  What is already known about this topic? COVID-19 vaccination during pregnancy is recommended to prevent severe illness and death in pregnant women. Infants are at risk for COVID-19–associated Complications, including respiratory failure and other life-threatening Complications.
  
  What is added by this report? Effectiveness of maternal completion of a 2-dose primary mRNA COVID-19 vaccination series during pregnancy against COVID-19 hospitalization among infants aged <6 months was 61% (95% CI = 31% to 78%). Effectiveness of completion of the primary COVID-19 vaccine series early and later in pregnancy was 32% (95% CI = –43% to 68%) and 80% (95% CI = 55% to 91%), respectively.
  
  What are the implications for public health practice? Completion of a 2-dose mRNA COVID-19 vaccination series during pregnancy might help prevent COVID-19 hospitalization among infants aged <6 months.
  
  Suggested citation for this article: Halasa NB, Olson SM, Staat MA, et al. Effectiveness of Maternal Vaccination with mRNA COVID-19 Vaccine During Pregnancy Against COVID-19–Associated Hospitalization in Infants Aged <6 Months — 17 States, July 2021–January 2022. MMWR Morb Mortal Wkly Rep. ePub: 15 February 2022.
  
  mm7107e3.htm?s_cid=mm7107e3_w
  
  mm7107e3-H.pdf
  
  
• Subjects:
  2019-nCoV Vaccine MRNA-1273 BNT162 Vaccine CoronaVirus Infections/Prevention & Control COVID-19 Vaccines COVID-19/Prevention & Control Humans Immunoglobulin G Infant, Newborn MRNA Vaccines Placenta Pregnancy Prospective Studies RNA, Messenger SARS-CoV-2 Vaccination Vaccines, Synthetic

  More +
• Source:
  MMWR: Morbidity and Mortality Weekly Report 2022; v. 71 Early Release
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Document Type:
  Journal Article
• Name as Subject:
  Moderna Covid-19 Vaccine ; Pfizer-BioNTech COVID-19 Vaccine
• Place as Subject:
  Arkansas ; California ; Colorado ; Georgia ; Illinois ; Indiana ; Louisiana ; Massachusetts ; Michigan ; Minnesota ; Missouri ; New Jersey ; North Carolina ; Ohio ; Pennsylvania ; South Carolina ; Texas
• Pages in Document:
  6 pdf pages
• Volume:
  71
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:f1f74b44d495bf12e63846b82714cd0ec36a55c8745cdc3e6c5198d7aac6dc1b55a6ceef37504556c78fafb1fa77556d66d46cea694b0ed0a4c6ef08ac51945f
• Download URL:
  https://stacks.cdc.gov/view/cdc/114451/cdc_114451_DS1.pdf
• File Type:
  [PDF - 249.35 KB ]