Anthropometric models to estimate fat mass at 3 days, 15 weeks and 54 weeks

Details

• Alternative Title:
  Pediatr Obes
• Personal Author:
  Gopalakrishnamoorthy, Mahalakshmi ; Whyte, Kathryn ; Horowitz, Michelle ; Widen, Elizabeth ; Toro-Ramos, Tatiana ; Johnson, Jill ; Gidwani, Sonia ; Paley, Charles ; Rosenn, Barak ; Lin, Susan ; Thornton, John ; Pi-Sunyer, Xavier ; Gallagher, Dympna
• Description:
  Background:
  
  Currently available infant body composition measurement methods are impractical for routine clinical use. The study developed anthropometric equations (AE) to estimate fat mass (FM, kg) during the first year using air displacement plethysmography (PEA POD® Infant Body Composition System) and Infant Quantitative Magnetic Resonance (Infant-QMR) as criterion methods.
  
  Methods:
  
  Multiethnic full-term infants (n=191) were measured at 3 days, 15 weeks, and 54 weeks. Sex, race/ethnicity, gestational age, age (days), weight-kg (W), length-cm (L), head circumferences-cm (HC), skinfold thicknesses mm [triceps (TRI), thigh (THI), subscapular (SCP), and iliac (IL)], and FM by PEA POD® and Infant-QMR were collected. Stepwise linear regression determined the model that best predicted FM.
  
  Results:
  
  Weight, length, head circumference and skinfolds of triceps, thigh and subscapular, but not iliac, significantly predicted fat mass throughout infancy in both the Infant QMR and PEA POD models. Sex had an interaction effect at 3 days and 15 weeks for both the models.
  
  Conclusions:
  
  Both PEAPOD and Infant-QMR derived models predict FM using skinfolds, weight, head circumference, and length with acceptable R2 and residual patterns.
  
  
• Subjects:
  Adipose Tissue Anthropometry Body Composition Humans Infant Plethysmography Skinfold Thickness Thigh
• Source:
  Pediatr Obes. 17(3):e12855
• Pubmed ID:
  34558804
• Pubmed Central ID:
  PMC8821135
• Document Type:
  Journal Article
• Funding:
  AT/NCCIH NIH HHSUnited States/ ; T32-DK065522/NH/NIH HHSUnited States/ ; CD/ODCDC CDC HHSUnited States/ ; K99/R00HD086304/NH/NIH HHSUnited States/ ; T32 DK065522/DK/NIDDK NIH HHSUnited States/ ; 5U01 DK094466/DK/NIDDK NIH HHSUnited States/ ; Indian Health Service,/ ; U01 DK094463/DK/NIDDK NIH HHSUnited States/ ; U01 HD072834/HD/NICHD NIH HHSUnited States/ ; T32-DK007559/NH/NIH HHSUnited States/ ; Indian Health Service/ ; U01 DK094466/DK/NIDDK NIH HHSUnited States/ ; U01 DK094418/DK/NIDDK NIH HHSUnited States/ ; T32 DK007559/DK/NIDDK NIH HHSUnited States/ ; NIH Office of Disease Prevention/ ; U01 HL114377/HL/NHLBI NIH HHSUnited States/ ; Office of the Director, National Institutes of Health/ ; U01 DK094416/DK/NIDDK NIH HHSUnited States/ ; NIH Office of Research on Women's Health/ ; R00 HD086304/HD/NICHD NIH HHSUnited States/ ; P30-DK026687/NH/NIH HHSUnited States/ ; T32 DK091227/DK/NIDDK NIH HHSUnited States/ ; NH/NIH HHSUnited States/ ; P30 DK026687/DK/NIDDK NIH HHSUnited States/ ; U01-DK094463/NH/NIH HHSUnited States/ ; Office of Behavioral and Social Science Research/ ; U01 HL114344/HL/NHLBI NIH HHSUnited States/ ; T32DK091227/NH/NIH HHSUnited States/ ; K99 HD086304/HD/NICHD NIH HHSUnited States/
• Volume:
  17
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:2975b22843ac8568718037c067aa4e4a28e1d78a808e0dd9ca2ba4e6b442c9d9
• Download URL:
  https://stacks.cdc.gov/view/cdc/114250/cdc_114250_DS1.pdf
• File Type:
  [PDF - 257.94 KB ]