Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2–Associated Deaths

Heinrich, Fabian; Schröder, Ann Sophie; Gerberding, Anna-Lina; Gerling, Moritz; Langenwalder, Felicia; Lange, Philine; Heinemann, Axel; Bibiza-Freiwald, Eric; Nörz, Dominik Sebastian; Aepfelbacher, Martin; Pfefferle, Susanne; Ondruschka, Benjamin; Lütgehetmann, Marc

doi:10.3201/eid2801.211749

i

Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2–Associated Deaths

Supporting Files Public Domain

1 2022
By Heinrich, Fabian ; Schröder, Ann Sophie ; Gerberding, Anna-Lina ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Heinrich, Fabian ; Schröder, Ann Sophie ; Gerberding, Anna-Lina ; Gerling, Moritz ; Langenwalder, Felicia ; Lange, Philine ; Heinemann, Axel ; Bibiza-Freiwald, Eric ; Nörz, Dominik Sebastian ; Aepfelbacher, Martin ; Pfefferle, Susanne ; Ondruschka, Benjamin ; Lütgehetmann, Marc
Description:

We investigated the infectivity of 128 severe acute respiratory disease coronavirus 2-associated deaths and evaluated predictive values of standard diagnostic procedures. Maintained infectivity (20%) did not correlate with viral RNA loads but correlated well with anti-S antibody levels. Sensitivity >90% for antigen-detecting rapid diagnostic tests supports their usefulness for assessment.
Subjects:

Autopsy Coronavirus Infections Covid-19 Diagnostic Tests, Routine Humans Sars-Cov-2 Sensitivity And Specificity Viral Load
Source:

Emerg Infect Dis. 2022; 28(1):244-247
Pubmed ID:

34726595
Pubmed Central ID:

PMC8714232
Document Type:

Journal Article
Volume:

28
Issue:

1
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:c077c3f4b8c88cf239a1e0730d2bab8d414f38a246d4ae20e781003959bb2433
Download URL:

https://stacks.cdc.gov/view/cdc/113343/cdc_113343_DS1.pdf
File Type:

[PDF - 1.24 MB ]

File Language:

English

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