i
Progress towards achieving hepatitis B control in the Cook Islands, Niue, Tokelau, and Kiribati
-
8 05 2016
-
-
Source: Vaccine. 34(36):4298-4303
[PDF-515.85 KB]
Details:
-
Alternative Title:Vaccine
-
Personal Author:
-
Description:Background:
Hepatitis B virus (HBV) is highly endemic in many of the Pacific Island countries. Four island countries—Cook Islands, Kiribati, Niue, and Tokelau—sought to evaluate the success of their hepatitis B vaccination programs by conducting nationally representative serosurveys among children born post-vaccine introduction.
Methods:
Cook Islands, Niue, and Tokelau conducted school-based census serosurveys because of small populations. The Cook Islands tested children in second grade; Niue tested children in early childhood education through sixth grade; and Tokelau tested children in first through sixth grades. Because Kiribati has a much larger birth cohort, it conducted a one-stage stratified serosurvey among first grade students. All four countries tested children using the Alere Determine™ rapid point of care hepatitis B surface antigen (HBsAg) test.
Results:
In the three smaller countries, no children were seropositive for HBsAg (0/245 Cook Island students, 0/183 Niuean students, 0/171 Tokelau students). In Kiribati, 39 (3.3%, 95% confidence interval 2.4–4.6%) of 1249 students were HBsAg positive. Vaccination data collected in the Cook Islands and Tokelau showed high vaccination coverage in both countries with ⩾P95% birth dose coverage and 100% 3-dose coverage.
Conclusions:
The Cook Islands, Niue, and Tokelau have made remarkable progress in establishing strong vaccination programs and towards decreasing the burden of hepatitis B among children. Kiribati still needs to improve vaccination coverage to achieve the <1% HBsAg target established by the World Health Organization Western Pacific Region.
-
Subjects:
-
Source:
-
Pubmed ID:27402565
-
Pubmed Central ID:PMC8735872
-
Document Type:
-
Funding:
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
