Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Grome, Heather N. ; Threlkeld, Michael ; Threlkeld, Steve ; Newman, Charles ; Martines, Roosecelis Brasil ; Reagan-Steiner, Sarah ; Whitt, Michael A. ; Gomes-Solecki, Maria ; Nair, Nisha ; Fill, Mary-Margaret ; Jones, Timothy F. ; Schaffner, William ; Dunn, John
• Description:
  We describe a fatal case of multisystem inflammatory syndrome in an adult with onset 22 days after a second dose of mRNA coronavirus disease vaccine. Serologic and clinical findings indicated severe acute respiratory syndrome coronavirus 2 infection occurred before vaccination. The immunopathology of this syndrome, regardless of vaccination status, remains poorly understood.
• Subjects:
  Adult Coronavirus Infections/Prevention & Control Covid-19 Vaccines Covid-19/Prevention & Control Humans Sars-Cov-2 Systemic Inflammatory Response Syndrome Vaccination
• Source:
  Emerg Infect Dis. 27(11):2914-2918
• Pubmed ID:
  34586059
• Pubmed Central ID:
  PMC8544993
• Document Type:
  Journal Article
• Funding:
  R01 AI139267/AI/NIAID NIH HHSUnited States/ ; R43 AI155211/AI/NIAID NIH HHSUnited States/
• Volume:
  27
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:a5ea64f47005e1f99068bacb514432c19b88b7a56dd8145ff08c50d2a83cd6cf
• Download URL:
  https://stacks.cdc.gov/view/cdc/111458/cdc_111458_DS1.pdf
• File Type:
  [PDF - 2.30 MB ]