Science brief: SARS-CoV-2 infection-induced and vaccine-induced immunity
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Science brief: SARS-CoV-2 infection-induced and vaccine-induced immunity



English
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Details:

  • Corporate Authors:
    National Center for Immunization and Respiratory Diseases (U.S.). Division of Viral Diseases.
  • Description:
    Updated Oct. 29, 2021

    This brief provides an overview of the current scientific evidence regarding infection-induced and vaccine-induced immunity, including both peer-reviewed and preprint publications, as well as unpublished CDC data. Although comprehensive, it is neither a formal systematic review nor meta-analysis. New data continue to emerge, and recommendations (the science brief, this webpage, etc.) will be updated periodically, as needed.

    Recovery from many viral infectious diseases is followed by a period of infection-induced immunologic protection against reinfection. This phenomenon is widely observed with many respiratory viral infections, including both influenza and the endemic coronaviruses, for which acquired immunity also wanes over time making individuals susceptible to reinfection.

    CDC continues to recommend COVID-19 vaccination for all eligible persons, including those who have been previously infected with SARS-CoV-2.

  • Content Notes:
    Executive Summary

    Background

    Immune Response to Infection and Vaccination -- Correlation of Immune Response Metrics to Protection -- Immune Response Kinetics and Duration of Protection -- Impact of Variants on Infection- and Vaccine-induced Immunity -- Comparison of Infection- and Vaccine-induced Immune Responses -- Vaccine-induced Immune Responses after Previous Infection -- Limitations -- Conclusions --References.

  • Subjects:
  • Series:
    Science brief
  • Document Type:
    Webpage
  • Collection(s):
  • Main Document Checksum:
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  • File Type:
    Filetype[PDF-1.32 MB]

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