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Science brief: evidence used to update the list of underlying medical conditions associated with higher risk for severe COVID-19
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Oct. 14, 2021
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Series: Science brief
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Description:Updated Oct. 14, 2021
Based on available literature and data from CDC-led investigations, we continue to learn more about COVID-19 and associated underlying medical conditions that put adults at higher risk of severe illness. Severe illness from COVID-19 is defined here as hospitalization, admission to the intensive care unit (ICU), intubation or mechanical ventilation, or death. Evidence used to inform this list was determined by CDC reviewers based on available evidence about COVID-19 at time of review.
The methods used to assess underlying medical conditions have changed during the pandemic as the amount of literature and types of studies grow. For instance, preliminary versions of this list focused on providing the latest information based on descriptive data. As the literature grew, CDC investigators categorized the literature by study design. Since May 2021, the process has been updated to include a CDC review process that uses rigorous systematic review methods.
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Content Notes:Context -- Overview -- Table of Evidence.
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[PDF-1.83 MB]
