Severity of Disease Among Adults Hospitalized with Laboratory-confirmed COVID-19 Before and During the Period of SARS-CoV-2 B.1.617.2 (Delta) Predominance — COVID-NET, 14 States, January–August 2021

Details

• Personal Author:
  Taylor, Christopher A. ; Patel, Kadam ; Pham, Huong ; Whitaker, Michael ; Anglin, Onika ; Kambhampati, Anita K. ; Milucky, Jennifer ; Chai, Shua J. ; Kirley, Pam Daily ; Alden, Nisha B. ; Armistead, Isaac ; Meek, James ; Yousey-Hindes, Kimberly ; Anderson, Evan J. ; Openo, Kyle P. ; Teno, Kenzie ; Weigel, Andy ; Monroe, Maya L. ; Ryan, Patricia A. ; Henderson, Justin ; Nunez, Val Tellez ; Bye, Erica ; Lynfield, Ruth ; Poblete, Mayvilynne ; Smelser, Chad ; Barney, Grant R. ; Spina, Nancy L. ; Bennett, Nancy M. ; Popham, Kevin ; Billing, Laurie M. ; Shiltz, Eli ; Abdullah, Nasreen ; Sutton, Melissa ; Schaffner, William ; Talbot, H. Keipp ; Ortega, Jake ; Price, Andrea ; Garg, Shikha ; Havers, Fiona P.
• Corporate Authors:
  COVID-NET Surveillance Team. ; CDC COVID-19 Response Team ; General Dynamics Information Technology. ; California Emerging Infections Program. ; Centers for Disease Control and Prevention (U.S.)Career Epidemiology Field Officer Program. ; Colorado. Department of Public Health and Environment. ; Yale University. School of Public Health. Connecticut Emerging Infections Program. ; Emory University School of Medicine. ; Georgia Emerging Infections Program. ; Veterans Affairs Medical Center (Atlanta, Ga.). ; Iowa. Department of Public Health. ; Maryland. Department of Health. ; Michigan. Department of Health and Human Services. ; Minnesota. Department of Health. ; New Mexico Emerging Infections Program, Albuquerque, New Mexico. ; New Mexico Department of Health. ; New York (State). Department of Health. ; University of Rochester School of Medicine and Dentistry. ; University of Rochester Medical Center. Rochester Emerging Infections Program. ; Ohio. Department of Health. ; Oregon Health Authority. Public Health Division. ; Vanderbilt University Medical Center. ; Salt Lake County (Utah). Health Department.
• Description:
  What is already known about this topic? The SARS-CoV-2 B.1.617.2 (Delta) Variants is highly transmissible; however, whether it causes more severe disease in adults has been uncertain.
  
  What is added by this report? Analysis of COVID-NET data from 14 states found no significant increases in the proportion of hospitalized COVID-19 patients with severe outcomes during the Delta period. The proportion of hospitalized unvaccinated COVID-19 patients aged 18–49 years significantly increased during the Delta period.
  
  What are the implications for public health practice? Lower vaccination coverage in adults aged 18–49 years likely contributed to the increase in hospitalized patients during the Delta period. COVID-19 vaccination is critical for all eligible adults, including adults aged <50 years who have relatively low vaccination rates compared with older adults.
  
  Suggested citation for this article: Taylor CA, Patel K, Pham H, et al. Severity of Disease Among Adults Hospitalized with Laboratory-Confirmed COVID-19 Before and During the Period of SARS-CoV-2 B.1.617.2 (Delta) Predominance — COVID-NET, 14 States, January–August 2021. MMWR Morb Mortal Wkly Rep.
  
  mm7043e1.htm?s_cid=mm7043e1_w
  
  mm7043e1-H.pdf
  
  
• Subjects:
  Adult Betacoronaviru CoronaVirus Infections COVID-19 Hospitalization Humans Infant Infant, Newborn Male Pandemics Pneumonia, Viral Risk Factors SARS-CoV-2 Severity Of Illness Index Young Adult

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• Source:
  MMWR: Morbidity and Mortality Weekly Report 2021; v. 70 Early Release
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Document Type:
  Journal Article
• Place as Subject:
  California ; Colorado ; Connecticut ; Georgia ; Iowa ; Maryland ; Michigan ; Minnesota ; New Mexico ; New York ; Ohio ; OregonTennessee ; Utah
• Pages in Document:
  7 pdf pages
• Volume:
  70
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:4e10a2f0f46a579eff281ebb4650436e2a065b207a1ab63ccdb85cb1393b5812ed156edef3d2ab6af81a8f281a06b66dd355773e2484027d2b9d17349fe858f6
• Download URL:
  https://stacks.cdc.gov/view/cdc/110990/cdc_110990_DS1.pdf
• File Type:
  [PDF - 290.18 KB ]