Therapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters

Williamson, Brandi N.; Prescott, Joseph; Garrido, Jose L.; Alvarez, Raymond A.; Feldmann, Heinz; Barría, Maria I.

doi:10.3201/eid2710.210735

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Therapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters

Supporting Files

2021/10/01
By Williamson, Brandi N. ; Prescott, Joseph ; Garrido, Jose L.
http://dx.doi.org/10.3201/eid2710.210735
Series: Emerging Infectious Diseases

File Language:

English

Details

Journal Article:

Emerging Infectious Diseases
Personal Author:

Williamson, Brandi N. ; Prescott, Joseph ; Garrido, Jose L. ; Alvarez, Raymond A. ; Feldmann, Heinz ; Barría, Maria I.
Description:

Andes virus, an orthohantavirus endemic to South America, causes severe hantavirus cardiopulmonary syndrome associated with human-to-human transmission. No approved treatments or vaccines against this virus are available. We show that a combined treatment with 2 monoclonal antibodies protected Syrian hamsters when administered at midstage or late-stage disease.
Subjects:
Keywords:
Series:

Emerging Infectious Diseases
DOI:

http://dx.doi.org/10.3201/eid2710.210735
Pubmed ID:

34545791
Pubmed Central ID:

PMC8462347
Document Type:

Text ; Journal Article
Funding:

R43 AI138740/AI/NIAID NIH HHSUnited States/
Genre:

Journal Article
Place as Subject:

South America
Rights:

Public Domain
Topic:

Diseases & Conditions
Location:

North America
Pages in Document:

4 pdf pages
Volume:

27
Issue:

10
Citation:

Emerg Infect Dis. 27(10):2707-2710
Download URL:

https://stacks.cdc.gov/view/cdc/110434/cdc_110434_DS1.pdf
File Type:

[PDF - 1.34 MB]
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha-512:16dffcd1d4d69440a0488a46932171be43ca3b8e7706d43a75f9f43d0f6a4f80ce7994f5bd14abb109693df0e784bec39f38ff008048d75d1b59797535dfe220

File Language:

English

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