Distribution and Characteristics of Human Plague Cases and Yersinia pestis Isolates from 4 Marmota Plague Foci, China, 1950–2019

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  He, Zhaokai ; Wei, Baiqing ; Zhang, Yujiang ; Liu, Jun ; Xi, Jinxiao ; Ciren, Dunzhu ; Qi, Teng ; Liang, Junrong ; Duan, Ran ; Qin, Shuai ; Lv, Dongyue ; Chen, Yuhuang ; Xiao, Meng ; Fan, Rong ; Song, Zhizhong ; Jing, Huaiqi ; Wang, Xin
• Description:
  We analyzed epidemiologic characteristics and distribution of 1,067 human plague cases and 5,958 Yersinia pestis isolates collected from humans, host animals, and insect vectors during 1950-2019 in 4 Marmota plague foci in China. The case-fatality rate for plague in humans was 68.88%; the overall trend slowly decreased over time but fluctuated greatly. Most human cases (98.31%) and isolates (82.06%) identified from any source were from the Marmota himalayana plague focus. The tendency among human cases could be divided into 3 stages: 1950-1969, 1970-2003, and 2004-2019. The Marmota sibirica plague focus has not had identified human cases nor isolates since 1926. However, in the other 3 foci, Y. pestis continues to circulate among animal hosts; ecologic factors might affect local Y. pestis activity. Marmota plague foci are active in China, and the epidemic boundary is constantly expanding, posing a potential threat to domestic and global public health.
• Subjects:
  Animals Humans Insect Vectors Marmota Plague Yersinia Pestis
• Source:
  Emerg Infect Dis. 27(10):2544-2553
• Pubmed ID:
  34545784
• Pubmed Central ID:
  PMC8462326
• Document Type:
  Journal Article
• Place as Subject:
  China
• Location:
  Asia
• Volume:
  27
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:71b5d268263746ee57a297070c1563ab0e8e7ee908f83d590311350d83925f81
• Download URL:
  https://stacks.cdc.gov/view/cdc/110410/cdc_110410_DS1.pdf
• File Type:
  [PDF - 3.02 MB ]